The Effectiveness of Using Fertile Chip on Intracytoplasmic Sperm Injection Undergoing Ivf Programme in Unexplained Infertile Couples
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 122
- 试验地点
- 1
- 主要终点
- increase fertilisation rate
研究概览
简要总结
The aim of the current study is to evaluate to effectiveness of sperm selection by using fertile chip in unexplained infertile couples on intracytoplasmic sperm injection (ICSI) cycles.
详细描述
The aim of the current study is to evaluate to effectiveness of sperm selection by using fertile chip in unexplained infertile couples on intracytoplasmic sperm injection (ICSI) cycles. On study arm sperm selection will be performed by using special microchannel system which is called fertile chip (FC) without using sperm wash procedure. This FC system leads to select lineer motile progressive sperm selection. In control group, sperm selection will be performed by classical way which sperm will be undertaken to sperm wash by gradient method.
After selection of sperm in both arms, ICSI will be performed. The outcomes of ICSI schedule will be assesed by fertilization and clinical pregnancy rates.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 20 Years 至 40 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •between 20-37 year-old women
- •normal tubal patency, normal uterine cavity, normal ovulation,
- •between 20-40 year-old men
- •normal semen analyse by WHO criterias
- •unexplained infertile couples
排除标准
- •poor ovarian reserve which is diagnosed by Bologna criterias
- •abnormal semen analyse by WHO sperm criterias
- •abnormal ovulation problems,tubal patency or uterine cavity
结局指标
主要结局
increase fertilisation rate
时间窗: 2 days
次要结局
- Clinical pregnancy rates(10 months)
研究者
Selçuk Yetkinel
Clinical Doctor
Baskent University