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临床试验/NCT07726394
NCT07726394已完成不适用

Effects of a Six-Day Whole-Diet Intervention on Taste Perception, Dietary Behaviour, and Individual Differences in Young Adults

Sunway University1 个研究点 分布在 1 个国家目标入组 115 人开始时间: 2026年4月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
115
试验地点
1
主要终点
Pleasantness

研究概览

简要总结

This study aims to investigate the effects of a specific diet modification on the pleasantness, desire, and saltiness intensities of selected foods and an ad libitum breakfast buffet through a randomized controlled trial with three arms. Participants will be randomized to either increase, decrease, or make no change to their daily intake of foods with a specific taste for six consecutive days, and outcomes will be assessed at two time points, at baseline (Day 1) and after the intervention (Day 7), alongside measures of adherence to the assigned diet. Each participant will receive an instruction to modify specific aspects of their diets for six days. This study is crucial for addressing diet-related health issues such as obesity, diabetes, and hypertension in Malaysia. By providing robust evidence on the effectiveness of specific diet modifications, the study can inform public health policies, improve dietary recommendations tailored to Malaysian cultural preferences, and promote long-term benefits.

详细描述

Excess dietary sodium intake is a major modifiable risk factor for hypertension and cardiovascular disease. Public health strategies often assume that reducing exposure to salty foods will lower salt preference and encourage healthier food choices through sensory adaptation; however, evidence from whole-diet interventions conducted under real-world conditions remains limited and inconsistent. Dietary sodium consumption substantially exceeds recommended levels in many countries, including Malaysia, and contributes to the global burden of hypertension and cardiovascular disease. Public health sodium reduction programmes are based on the premise that lowering exposure to salty foods can gradually shift taste preferences towards less salty diets through sensory adaptation. However, evidence supporting this mechanism is mixed, and most previous studies have relied on controlled laboratory settings, single foods, or salt solutions rather than whole-diet interventions.

The study aims to determine whether short-term changes in dietary sodium exposure are sufficient to modify salt taste perception and related eating behaviors and to identify factors associated with individual variation in these responses. The primary objective is to determine whether increasing or decreasing exposure to salty foods over six days alters salt-related taste perception compared with maintaining usual dietary habits. Secondary objectives are to examine changes in sodium intake and appetite-related outcomes and to explore demographic and anthropometric factors associated with taste perception responses. The findings will improve understanding of short-term sensory adaptation to dietary sodium exposure and provide evidence relevant to sodium reduction policies, food reformulation efforts, and behavioral interventions aimed at reducing population sodium intake.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Prevention
盲法
Double (Participant, Investigator)

盲法说明

Allocation will be concealed throughout the study, and research assistants interacting directly with participants will remain blinded to group assignment. Participants will be instructed not to disclose their dietary instructions to the researchers to maintain blinding

入排标准

年龄范围
18 Years 至 35 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Being a student or staff member of Sunway University or Sunway College
  • Aged 18-35 years
  • Able to communicate in English
  • Regularly consuming breakfast
  • Being willing and able to comply with all study procedures.

排除标准

  • Vegan/smokers/with chronic medical conditions (e.g., hypertension or diabetes)
  • Food allergies
  • Pregnant or breastfeeding
  • Currently dieting or attempting to lose weight
  • History of smell or taste impairment
  • Use medications or supplements that could affect taste perception.

研究组 & 干预措施

Increase salty food consumption

Experimental

Participants increase intake of salty foods and beverages.

干预措施: Experimental: Increased Salty Food Intake (Other)

Decrease salty food consumption

Experimental

Participants decrease intake of salty foods and beverages.

干预措施: Experimental: Decrease Salty Food Intake (Other)

Maintain usual diet

Active Comparator

Participants continue their habitual dietary practices

干预措施: Active Comparator: Maintain Usual Diet (Other)

结局指标

主要结局

Pleasantness

时间窗: Pleasantness ratings will be collected at baseline (Day 1) and Day 7

Pleasantness ratings, indicated after tasting three salty foods (Foods 1-3) and three non-salty foods (Foods 4-6), will be measured on a 10-point Likert scale. The rating scores will be averaged across the six test foods to generate composite scores. The aggregated pleasantness score will be used to capture overall taste responses rather than food-specific effects, consistent with whole-diet taste exposure theory.

Desire to eat

时间窗: Desire to eat ratings will be collected at baseline (Day 1) and Day 7

Desire to eat ratings, indicated after tasting three salty foods (Foods 1-3) and three non-salty foods (Foods 4-6), will be measured on a 10-point Likert scale. The rating scores will be averaged across the six test foods to generate composite scores. The aggregated pleasantness score will be used to capture overall taste responses rather than food-specific effects, consistent with whole-diet taste exposure theory.

Saltiness intensity

时间窗: Saltiness intensity ratings will be collected at baseline (Day 1) and Day 7

Saltiness intensity ratings, indicated after tasting three salty foods (Foods 1-3) and three non-salty foods (Foods 4-6), will be measured on a 10-point Likert scale. The rating scores will be averaged across the six test foods to generate composite scores. The aggregated pleasantness score will be used to capture overall taste responses rather than food-specific effects, consistent with whole-diet taste exposure theory.

次要结局

  • Dietary sodium intake(Dietary sodium intake is estimated at baseline (Day 1) and Day 7)
  • Sodium Density(Sodium density will be assessed at baseline (Day 1) and Day 7)
  • Appetite(Appetite will be assessed at the baseline (Day 1) and Day 7)
  • Adherence(Adherence was assessed only on Day 7)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

YookChin Chia

Professor

Sunway University

研究点 (1)

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