NCT00002054已完成不适用
A Double-Blind Study To Evaluate the Long-Term Safety and Effectiveness of 60 mg Versus 120 mg of Aerosol Pentamidine in the Prophylaxis of Pneumocystis Carinii Pneumonia in AIDS Patients
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- Fisons
- 试验地点
- 2
研究概览
简要总结
To evaluate the safety, tolerability, and description of time to Pneumocystis carinii pneumonia (PCP) for long-term biweekly administration of 1 of 2 doses of aerosol pentamidine when used as a prophylactic agent in patients who have had one episode of AIDS-associated PCP.
研究设计
- 研究类型
- Interventional
- 主要目的
- Treatment
- 盲法
- Double
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients who have completed 16 treatments under Fisons study no. 87-71 entitled, "A Double-Blind Group Comparative Study To Evaluate the Safety and Effectiveness of Three Different Doses of Aerosol Pentamidine in the Prophylaxis of Pneumocystis Carinii Pneumonia in Patients With AIDS Post First Episode PCP." Detailed safety parameters must have been documented for 6 months.
- •Patients must receive the first dose on this study within 2 weeks of their last dose under study no. 87-71.
排除标准
- •Co-existing Condition:
- •Patients with the following are excluded:
- •Requiring ongoing active therapy for an opportunistic infection (O.I.) at time of entry or those patients with either of the following AIDS-defining O.I.'s at entry:
- •Toxoplasmosis.
- •Cryptococcosis.
- •Pulmonary Kaposi's sarcoma.
- •Asthma poorly controlled by medication.
- •Receiving active therapy for tuberculosis.
- •Patients with the following are excluded:
- •Requiring ongoing active therapy for an opportunistic infection (O.I.) at time of entry or those patients with either of the following AIDS-defining O.I.'s at entry:
- •Toxoplasmosis.
- •Cryptococcosis.
- •Pulmonary Kaposi's sarcoma.
- •Unwilling to sign informed consent.
- •Cannot cooperate with study procedures.
- •Asthma poorly controlled by medication.
- •Receiving active therapy for tuberculosis.
- •Active substance abuse.
研究者
研究点 (2)
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