DRKS00026082进行中（未招募）未知
Cytokine adsorption in patients with acute on chronic liver failure (CYTOHEP) – a single center, open-label, randomized, controlled intervention trial - CYTOHEP
niversitätsklinikum Freiburg Department Innere Medizin Klinik für Innere Medizin III0 个研究点目标入组 9 人开始时间: 2021年8月24日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 9
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized controlled study
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 18 Years 至 one（—）
- 性别
- All
入选标准
- •Adult patients (= 18 years) admitted to the University Medical Center Freiburg, Germany
- •- acute-on-chronic liver failure (ACLF) WITH
- •a) acute kidney injury according to Kidney Disease: Improving Global Outcome (KDIGO) criteria stage 3 (= 3-fold increase of serum creatinine OR increase of serum creatinine to = 4 mg/dl OR urine output = 0.3 ml/kg/h for = 24 hours OR anuria for = 12 hours) AND
- •b) serum bilirubin = 5 mg/dl
排除标准
- •- known patient will against participation in the study or against the measures applied in the study
- •- a decision made prior to inclusion to stop further treatment of the patient within the next 24 hours
- •- no complete remission of malignancy including hepatocellular carcinoma within the past 12 months
- •- patients on the waiting list for liver transplant or the potential option for being listed for liver transplant within the next 6 months
- •- liver cirrhosis in patients after liver transplantation
- •- ongoing intermittent or continuous renal replacement therapy before study inclusion
研究者
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