Weight in Lower Limbs Improves Gait Ataxia Of in Machado-Joseph Disease Patients: A Randomized Crossover Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 20
- 主要终点
- Gait speed analysis [speed (mt/min) of walking for 10 meters away]
研究概览
简要总结
Few studies evaluated the efficacy of adding weights on the lower limbs in patients with ataxic disorders. There is no current evidence on which would be the most appropriate weight for use in this context. To assess progress and benefits of using this load, gait of symptomatic carriers of spinocerebellar ataxia type 3/Machado Joseph disease the objective of the study is to evaluate the gait with and without different load weights on lower limbs. Outcomes were the Scale for the Assessment and Ataxia Rating of (SARA), kinematic gait assessment by the accelerometer and gyroscope and the Patient Global Impression (PGI) about which weight they prefer for walking.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients should have between 18 and 65 years of age and independent gait
排除标准
- •Were the need of assistive devices for walking ≤ 10m (such as crutches, wheelchairs and orthotics)
- •Item gait of Scale for the Assessment and Rating of Ataxia (SARA)19≥, presence of other neurological disease that affect motor system
- •Orthopedic impairments of lower limbs (fractures or surgeries in the past 6 months)
- •Difference between the lower limbs greater than 3.0 cm
结局指标
主要结局
Gait speed analysis [speed (mt/min) of walking for 10 meters away]
时间窗: speed (mt/min) of walking for 10 meters away in 1min timeout
次要结局
- Gait cadence analysis [cadence (steps/min) of walking for 10 meters away](cadence (steps/min) of walking for 10 meters away in 1min timeout)
研究者
giovana duarte eltz
Physiotherapist
Federal University of Health Science of Porto Alegre