JPRN-UMIN000019067招募中未知
The role of Growth differentiation factor 11 in the pathogenesis of chronic obstructive pulmonary disease - The role of Growth differentiation factor 11 in the pathogenesis of chronic obstructive pulmonary disease
Department of Respiratory Medicine, TohokuUniversityGraduateSchoolof Medicine0 个研究点目标入组 300 人开始时间: 2015年9月18日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 招募中
- 发起方
- 入组人数
- 300
研究概览
简要总结
The levels of GDF11 are decreased in both the plasma and lungs of COPD patients, and inversely correlate with the severity of the airflow limitation; treatment with GDF11 inhibits the cigarette smoke (CSE)-induced cellular senescence and production of inflammatory mediators in vitro.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 20years-old 至 ot applicable(—)
- 性别
- All
入选标准
- 未提供
排除标准
- •patients and healthy volunteers who deny participating in this study
研究者
相似试验
未知
不适用
Role of growth differentiation factor 11 in physical activity, exercise capacity and systemic inflammation of patients with COPDchronic obstructive pulmonary diseaseJPRN-UMIN000024105Department of Respiratory Medicine, TohokuUniversityGraduateSchoolof Medicine300
已完成
不适用
Pulmonary and Systemic Hepatocyte Growth Factors in Patients With COPDChronic Obstructive Pulmonary DiseaseNCT00477074Hospital Universitari Son Dureta44
已完成
不适用
Regulation of Inflammatory Mediators in Chronic Obstructive Pulmonary DiseaseCOPDEmphysemaNCT00147095Imperial College London80
撤回
不适用
GR Defect in Sputum Cells in COPDChronic Obstructive Pulmonary Disease (COPD)NCT00159276Imperial College London
已完成
不适用
Role of Fibrocytes in Chronic Obstructive Pulmonary DiseaseChronic Obstructive Pulmonary DiseaseNCT01196832University Hospital, Bordeaux115
