Effect of Early Analgesic Treatment on Opioid Consumption
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 1,500
- 主要终点
- use of rescue opioids
研究概览
简要总结
introduction: Pain remains one of the most common reasons of emergency department admission. Opioids are overprescribed in emergency departments to treat severe pain.
objective: assessing the impact of ealy pain pain management on the use of intravenous morphine and on patient satisfaction.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •over 18 years of age
- •a visual analog scale (VAS) equal to or higher than 30/100 ,
- •having given consent to participation
- •No contraindications to products used in the course of the study.
排除标准
- •having a vital distress that does not allow an adequate assessment of the intensity of the pain
- •an inability to assess pain intensity according to the VAS,
- •swallowing disorders or inability , or a contraindication or an allergy to the treatments used.
研究组 & 干预措施
group Placebo
Patients in this group (Placebo Oral Tablet) received two placebo tablets
干预措施: Placebo Oral Tablet (Drug)
group Paracetamol
Patients in this group received two 500 mg paracetamol tablets
干预措施: Paracetamol (Drug)
group Tramadol/Paracetamol combination
Patients in this group (Tramadol/Paracetamol combination ) received 2 tablets of Tramadol/Paracetamol combination (37.5mg/325mg)
干预措施: Tramadol/Paracetamol combination (Drug)
结局指标
主要结局
use of rescue opioids
时间窗: DURING emergency department stay
decreased consumption of intravenous morphine
次要结局
- patient satisfaction(When quitting emergency department)
- Length of emergency department stay(Until emergency department discharge)
- Pain intensity at emergency department discharge(At emergency department discharge)
研究者
Pr. Semir Nouira
professor
University of Monastir