NCT03927430已完成不适用
To Peel or Not to Peel: Surgical Outcome of Macular Membrane Peeling Associated With Significant Macular Drusen
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- number of patients with CNV
研究概览
简要总结
Surgical outcome of patients with macular drusen and co-existing abnormalities of the vitreoretinal interface, who routinely undergo pars plana vitrectomy with membrane peeling, is evaluated. Best corrected visual acuity as well as optical coherence tomography data are compared at baseline and last follow up. The rate of development of choroidal neovascularization postoperatively is noted.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •participants diagnosed with ERM or FTMH and co-existing macular drusen;
- •undergone pars plana vitrectomy with ILM and epiretinale membrane peeling;
- •SD-OCT at the initial visit and at last follow up visit with image quality score >30;
- •no evidence of CNV on initial fluorescein angiography (FA).
排除标准
- •history of other macular disease, severe non-proliferative or proliferative diabetic retinopathy, other retinal vascular diseases, glaucoma, myopic retinopathy, or other diseases interfering with OCT images in any one of the eyes;
- •active CNV or history of CNV
结局指标
主要结局
number of patients with CNV
时间窗: last visit, in common 6 months postoperatively
number of patients with CNV (choroidal neovascularization) development
次要结局
- incidence of central retinal atrophy(last visit, in common 6 months postoperatively)
- BCVA(last visit, in common 6 months postoperatively)
研究者
Katrin Engelmann
Head of Ophthalmology
Klinikum Chemnitz gGmbH
研究点 (1)
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