跳至主要内容
临床试验/NCT06925308
NCT06925308招募中不适用

Course of Face-to-face Interactions in Adults With Autism: An Exploratory Mixed Methods Experimental Design

UMC Utrecht2 个研究点 分布在 1 个国家目标入组 54 人开始时间: 2025年2月3日最近更新:

试验速览

阶段
不适用
状态
招募中
发起方
UMC Utrecht
入组人数
54
试验地点
2
主要终点
Frequency of eye contact in adults with autism, measured with video, audio and push button.

研究概览

简要总结

This research explores how adults with autism make eye contact during formal and informal interactions; to what extent the nature of a conversation influences how eye contact is made in terms of length, frequency and overall presentation. Also what physiological responses to eye contact are, in order to determine to what extent eye contact leads to an increased, decreased or unchanged stress level. In addition, to gain insight into the similarities and differences in how people with ASD respond to eye contact of others compared to their own eye contact.

详细描述

This research explores how adults with autism make eye contact during formal and informal interactions; to what extent the nature of a conversation influences how eye contact is made in terms of length, frequency and overall presentation. Also what physiological responses to eye contact are, in order to determine to what extent eye contact leads to an increased, decreased or unchanged stress level. In addition, to gain insight into the similarities and differences in how people with ASD respond to eye contact of others compared to their own eye contact.

The research design chosen is an exploratory mixed methods study, which was developed in co-design with an expert by experience. The design consists of two parts. In the first part, the researcher will have a conversation (with a formal and informal phase, in which the subject will be given the idea that only the formal part is part of the research) with an adult with ASD, during which hidden recordings of the subject's eye behavior will be made, and in addition, skin conductance and duration/frequency of the subject's eye contact will be recorded, without the subject knowing that this is intended for research into eye contact. In the second part, the researcher and subject watch the hidden recording of the subject's eye behavior, during which the subject's skin conductance will be recorded and special features of the subject, as seen by the researcher. Both the arrangement of the subjects and researcher, as well as the physiological measurements, will be tested in advance.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Treatment
盲法
None

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Neurotypical adults and adults with an ASD, determined according to an internationally recognized classification system.
  • Able to understand the instructions.
  • Motivation to participate in research.

排除标准

  • No good command of the Dutch language.
  • Use of alcohol and/or recreational drugs during the research.
  • Mentally too unstable to participate in the research.
  • Familiarity with treatment in the VGZ.

结局指标

主要结局

Frequency of eye contact in adults with autism, measured with video, audio and push button.

时间窗: Baseline

The research consists of two parts. During the first part, the conversation, the frequency of eye contact will be investigated. This will be measured by video recordings of the eye region combined with the pressing of a push button by the researcher at moments when eye contact is present. Data will be analyzed using software programs Observer XT and Matlab for the integration of push button, video recordings and audio recordings.

Duration of eye contact in adults with autism, measured with video, audio and push button.

时间窗: Baseline

The research consists of two parts. During the first part, the conversation, the duration of eye contact will be investigated. This will be measured by video recordings of the eye region combined with the pressing of a push button by the researcher at moments when eye contact is present. Data will be analyzed using software programs Observer XT and Matlab for the integration of push button, video recordings and audio recordings.

Arousal during eye contact in adults with autism, measured with skin conductance

时间窗: Baseline

The research consists of two parts. During the first part, the arousal during eye contact will be investigated. This will be measured by a skin conductance meter and analysed with the software program VSRRP.

Arousal during reflection on ones own eye contact in adults with autism, measured with skin conductance

时间窗: Baseline

During the second part, the reflection on video recordings of ones own eye contact in aduls with autism, the degree of arousal to seeing their own eye contact will be investigated. For this, skin conductance meter will be used and analysed with the software program VSRRP.

Reflection on ones own eye contact in adults with autism, measured with video and audio

时间窗: Baseline

During the second part, reflection first part, it will be investigated how subjects respond with words. For this, audio and video recordings will be used. Data analysis will be conducted with use of thematic analysis and software programs Atlas.ti, Microsoft Excel and Microsoft Word.

次要结局

未报告次要终点

研究者

发起方
UMC Utrecht
申办方类型
Other
责任方
Principal Investigator
主要研究者

Jos Boer

MSc

UMC Utrecht

研究点 (2)

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