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临床试验/CTRI/2023/08/056753
CTRI/2023/08/056753尚未招募4 期

Comparative evaluation of neuromuscular monitoring at the adductor pollicis and trapezius muscle as indicator of favourable intubating conditions

MAX SUPER SPECIALITY HOSPITAL1 个研究点 分布在 1 个国家目标入组 70 人开始时间: 2023年8月31日最近更新:

试验速览

阶段
4 期
状态
尚未招募
入组人数
70
试验地点
1
主要终点
onset time of neuromuscular block at the APM & trapezius muscle for endotracheal intubation

研究概览

简要总结

This is a randomized, prospective clinical trial comparing onset of neuromuscular block at adductor pollicis and trapezius muscle after injection of rocuronium in 70 ASA I-II patients undergoing general anaesthesia. The purpose of the trial is to look for favourable intubating conditions after rocuronium injection.

Aim of this study is to evaluate trapezius muscle as indicator of favourable intubating conditions after neuromuscular blockage compared to adductor pollicis muscle.During intubation, inadequate muscle relaxation can lead to increased sympathetic stimulation and poor CL grade. Hence finding the adequate dosage of neuromuscular blocking agents by using peripheral nerve stimulators at different  muscle groups can lead to better intubating conditions.

研究设计

研究类型
Interventional
分配方式
Computer generated randomization
盲法
Participant and Investigator Blinded

入排标准

年龄范围
18.00 Year(s) 至 90.00 Year(s)(—)
性别
All

入选标准

  • ASA grade I,II
  • Patients giving consent for the study.

排除标准

  • Patients refusing to give consent for the study
  • ASA Physical Status Classification ≥ III
  • Patients requiring an awake intubation
  • Allergies to drugs administered during the study
  • Neuromuscular disease.

结局指标

主要结局

onset time of neuromuscular block at the APM & trapezius muscle for endotracheal intubation

时间窗: 5 MINUTES

次要结局

  • To assess for acceptable intubation conditions using CL grade, vocal cord & diaphragmatic movements during laryngoscopy(5 MINUTES)

研究者

申办方类型
Private hospital/clinic

研究点 (1)

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