NCT07170761进行中（未招募）不适用
Cross-sectional Biomarker Study for Vascular Calcification in Hemodialysis Patients
Medical University of Graz1 个研究点 分布在 1 个国家目标入组 475 人开始时间: 2022年10月15日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 475
- 试验地点
- 1
- 主要终点
- Mortality
研究概览
简要总结
Parathyroid hormone (PTH) remains the central biomarker to classify CKD-metabolic bone disease (CKD-MBD) in hemodialysis patients. While PTH-values are known to be associated with adverse outcomes, interventional studies have failed to show a benefit of pharmacological modulation of PTH levels on hard clinical outcomes. To address this gap, the investigators explored alternative markers of bone metabolism, vascular calcification and inflammation in association to prospective event patterns.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 100 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Stable hemodialysis > 3 months duration
排除标准
- •Pregnancy
- •Acute infections or antibiotic treatment (within 4 weeks)
结局指标
主要结局
Mortality
时间窗: 1, 2 and 3 years
All-causes, the date of death will be recorded.
次要结局
- MACE(1, 2 and 3 years)
- Cause-specific mortality(1, 2 and 3 years)
- The number of participants with hospitalisation for Infection(1, 2 and 3 years)
- The number of participants with hospitalisation for Heart failure(1, 2 and 3 years)
- The number of participants with Fractures(1, 2 and 3 years)
- The number of participants with Bleeding events(1, 2 and 3 years)
- The number of participants with Interventions for vascular diseases(1, 2 and 3 years)
研究者
研究点 (1)
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