Systematic Calculation of HyperOxygenation Transit Time Mesure transcutanée de l'oxygène au Cours de l'Hyperoxie Transitoire
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 发起方
- 入组人数
- 1
- 试验地点
- 1
- 主要终点
- Estimation of transcutaneous oxymetry with transient hyperoxia
研究概览
简要总结
Cardiac output (CO) is an essential physiological parameter of healthy person or illness.
In clinical practices, all methods of measuring the CO(Fick method, thoracic impedance, esophageal echodoppler etc) contain limit. Each method are dangerous or hard to implement.
CO is probably determining element of blood transit time and thus the availability of oxygen between the central organs (heart, lung) and the peripheral organs (leg, arms).
Our hypothesis is transcutaneous oxymetry mesurement with oxygen inhalation, to cause a transient hyperoxia, can be used to determinate blood transit time between central organs and peripheral organs. This simple method will be non invasive technique.
详细描述
At admission eligible patients are proposed to participate. Written consent is signed after complete oral and written explanation of the protocol is signed.
The time of onset hyperoxia will be compare to usual CO method by cross correlation.
The duration of participation for subject is equal to 1 hour.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Adults over 18
- •Cardiac output measurement considered at least 2 hours prior to the study
- •Affiliation to a French National healthcare system
- •Written informed consent must be obtained prior to protocol-specific
排除标准
- •Acute or decompensated cardiac or respiratory failure
- •Allergy to medical adhesives
- •Patients under reinforced protection, pregnancy, deprived of liberty by judicial or administrative decision, hospitalized without consent or admitted to a health or social establishment for purposes other than research
- •Inability to understand the instructions or objectives of the study
研究组 & 干预措施
Cardiac Output Measurement
Subject will have a usual cardiac output
干预措施: Transcutaneous oxymetry measurement (Diagnostic Test)
结局指标
主要结局
Estimation of transcutaneous oxymetry with transient hyperoxia
时间窗: 24 months
Transition time calcutation from oxygen to peripheral organs by transcutaneous oxymetry method.
Average of CO measured
时间窗: 24 months
Average of CO by usual method (catheterisation or transoesophageal echocardiography) reported in medical record of patients
次要结局
未报告次要终点