Minimal Occlusive Pressure With Cuffed ETTs: A Comparison of Two Different Techniques to Ensure a Tracheal Seal
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 2
- 主要终点
- Intracuff pressure
研究概览
简要总结
In the past 5 years cuffed endotracheal tubes (ETT) have become the standard of care in pediatrics. However, hyperinflation of the cuff can compromise the tracheal mucosal perfusion while an inadequate seal may impact ventilation and potentially increase the risk of aspiration. Hence, the goal after placement of a cuffed ETT is to create a safe and effective tracheal seal. The two ways to measure that are to hold CPAP while listening for an audible leak and measuring the difference between the inspired and expired tidal volumes (TV). This is a prospective study to compare these two methods used to create a tracheal seal and measure the intracuff pressure after a satisfactory tracheal seal is established.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Children who are scheduled to undergo GA with a cuffed ETT in place.
排除标准
- •Any children with pre-existing tracheal/bronchial anomalies, patients with Down syndrome, patients with C-spine issues.
结局指标
主要结局
Intracuff pressure
时间窗: Immediately following intubation
Difference in intracuff pressure measured after inflation with CPAP and inflation with TV.
次要结局
未报告次要终点
研究者
Senthil G. Krishna
Assistant Professor
Nationwide Children's Hospital