NCT02913651已完成不适用
Cardiovascular Variability and Heart Rate Arousal Response in Idiopathic Hypersomnia
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 33
- 试验地点
- 1
- 主要终点
- High Frequencies (HF)
研究概览
简要总结
Autonomic nervous system dysfunction has been described in narcolepsy with cataplexy affecting the sympathetic function. In this study the investigators analyzed whether altered diurnal and nocturnal cardiovascular control is present in idiopathic hypersomnia. Drug-free patients diagnosed with idiopathic hypersomnia and age-matched controls were included. Clinical data, 24-h polysomnography, heart rate variability and the heart rate response to spontaneous arousal are analyzed.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Idiopathic hypersomnia patients
- •idiopathic hypersomnia diagnosis
- •complaints of excessive daytime sleepiness for >1 year
- •a night-time length >10 h for 3 weeks before polysomnography as assessed by a sleep diary
- •Inclusion Criteria:
- •no idiopathic hypersomnia patients
- •no sleep complaints and excessive daytime sleepiness (Epworth sleep questionnaire score <10
- •Exclusion Criteria (both):
- •Narcolepsy-cataplexy
- •sleep irregularities and sleep deprivation symptoms
- •lack of neurological or psychiatric diseases
- •upper airway resistance syndrome
- •periodic limbs movements
- •cerebral lesion
- •medication or drinks affecting sleep and wake state
排除标准
- 未提供
结局指标
主要结局
High Frequencies (HF)
时间窗: During the polysomnography (one night)
Nocturnal parasympathetic activity (HF parameter of heart rate variability analysis)
次要结局
- Heart rate variability (HRV)(During the polysomnography (one night))
- Apnea-Hypopnea Index (AIH)(During the polysomnography (one night))
- Epworth Sleepiness Scale (ESS)(Before the polysomnography (one night))
研究者
研究点 (1)
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