A Comparative Study on the Cost-effectiveness of Four Methods in Preventing Fissure Caries in Permanent Teeth
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 329
- 试验地点
- 1
- 主要终点
- dental caries
研究概览
简要总结
The aim of this proposed study is to investigate the cost-effectiveness of four methods in preventing fissure caries in permanent teeth, which is the most prevalent dental disease in primary school children in China.
The four caries prevention methods are: resin fissure sealant, atraumatic restorative treatment (ART) sealant, sodium fluoride varnish, and silver diamine fluoride (SDF) solution.
The specific study objectives are:
- to describe longitudinally the clinical outcomes of using the above four methods to prevent dental caries in the pits and fissures of permanent first molars in school children,
- to describe the cost of using the above four methods to prevent dental caries in an outreaching dental care programme in China, and
- to compare the cost-effectiveness of the above four caries prevention methods.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 6 Years 至 9 Years（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •school children in good general health
- •has at least one pair of sound permanent first molars with deep occlusal fissures or fissures with signs of early caries
排除标准
- •children with major systemic disease or on long-term medication
- •children not cooperative and refuse dental treatments
研究组 & 干预措施
Resin dental sealant
Resin dental sealant placed on pits and fissures of first permanent molars, single-time placement and no replacement
干预措施: Resin dental sealant (Other)
ART dental sealant
ART dental sealant placed with glass ionomer material using the ART technique on permanent first molar, single-time placement and no replacement
干预措施: ART dental sealant (Other)
Sodium fluoride varnish
Topical application of 5% sodium fluoride varnish onto pits and fissures of permanent first molars, repeated every 6 months
干预措施: Sodium fluoride varnish (Other)
Silver fluoride solution
Topical application of 38% silver fluoride solution onto pits and fissures of permanent first molars, repeated every 12 months
干预措施: Silver fluoride solution (Other)
结局指标
主要结局
dental caries
时间窗: 3 years
development of carious cavity after 3 years
次要结局
未报告次要终点
研究者
LO, Edward Chin Man
Professor
The University of Hong Kong