Effect of Opioid Titration protocol using nociception monitors in gynecologic laparoscopic surgery with total hysterectomy: a Randomized Controlled Trial (OPTIMIST-h study)

未提供0 个研究点目标入组 75 人开始时间: 2024年3月25日最近更新: 2025年1月30日

试验速览

暂无简介。

•Female patients undergoing laparoscopic or robotic-assisted laparoscopic total hysterectomy
•Patients classified as American Society of Anesthesiologists physical status 1-2
•Patients between the ages of 20 and 85 years
•Patients who have given written consent to participate in the study

•Patients who are scheduled to undergo emergency surgery
•Patients who are being treated with a beta-blocker (oral intake or patch)
•Patients being treated with steroids
•Patients who cannot secure the measurement site due to amputated fingers or nail lesions
•Patients with a pacemaker
•Patients after heart transplantation
•Patients using drugs that affect sinus node (atropine, anticholinergic drugs)
•(8) Patients who are incapable of consenting
•Patients who are judged to be inappropriate as research subjects by the investigators responsible for the study.

Amount of intraoperative remifentanil usage

Total amount of remifentanil divided by the usagetime (min) and ideal body weight (kg)

Total amount of remifentanil administered during surgery(during surgery)
Comparison of biomarker values
Change in Quality of Recovery Score-15 values(day before surgery(Pre), postoperative day (POD) 1 and 2)
NRS (Numerical Rating Scale) values(day of surgery (2 hours postoperatively), at POD1, 2, 3 , and at 3 months after surgery)
Perioperative opioid (fentanyl) consumption(perioperative)
Presence of chronic postsurgical pain

发起方

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