Advancing Tools for Human Early Lifecourse Exposome Research and Translation- Adolescence Follow-up of the HELIX Subcohort
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 80
- 试验地点
- 2
- 主要终点
- Urinary biomarkers exposure
研究概览
简要总结
ATHLETE will set up a prospective Europe-wide exposome cohort covering the first 2 decades of the life course, which will integrate data on the external, chemical, physical,behavioral, and social domains of the exposome, as well as on health outcomes and biological omics responses, from preconception until adolescence. As part of ATHLETE, the investigators will follow up a unique existing exposome cohort into adolescence (the HELIX Subcohort).
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 16 Years 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •For the adolescent :
- •Subject of the EDEN cohort included in the Helix cohort in 2014-2015 in Poitiers (16-19 years old)
- •Subject benefiting from a Social Security scheme or benefiting through a third party
- •For the person legally responsible :
- •The legal guardian, if possible the mother, of the adolescent included in Athlete ;
- •Subject benefiting from a Social Security scheme or benefiting through a third person;
- •Free subject, without tutorship or guardianship or subordination.
排除标准
- •Concomitant participation in another clinical research study.
- •Persons not benefiting from a Social Security scheme or not benefiting through a third party.
- •Adolescents who are incapable or who do not give their consent to follow the study procedures
结局指标
主要结局
Urinary biomarkers exposure
时间窗: One week
Measure of phtalates, phenols, pesticides, (organophosphorus pesticides, metabolites of pyrethroids, 2,4-dichlorophenoxyacid, boscalid, imazalil), cotinine, glycol ethers, polycyclic aromatic hydrocarbon, creatinine, exogenous metabolomics, in a weekly pool of urine collection
次要结局
未报告次要终点