Building Respiratory Evidence for AI Tools and Health Equity (BREATHE)

Gates Foundation0 个研究点目标入组 18,000 人开始时间: 2026年8月1日最近更新: 2026年8月3日

适应症

试验速览

暂无简介。

•Age = 18 years
•Symptoms suggestive of TB (e.g., cough >2 weeks, weight loss, fever, night sweats)
•Known TB contact in the past 12 months with or without symptoms
•Person living with HIV (PLHIV) under TB evaluation with or without symptoms with available chest radiograph
•Adult Pneumonia:
•Age = 18 years
•Acute respiratory symptoms and signs (new or increased) (e.g., cough +/- fever +/- dyspnoea +/- pleuritic chest pain + tachypnoea or respiratory distress) suggestive of pneumonia
•Paediatric TB:
•Age < 18 years
•Symptoms suggestive of TB (e.g., persistent cough, fever >2 weeks, weight loss/ failure to thrive)
•Known TB contact in the past 12 months with or without symptoms
•Child living with HIV (CLHIV) under TB evaluation with or without symptoms
•Paediatric Pneumonia:
•Age < 18 years
•Acute respiratory symptoms (e.g., cough or difficulty breathing AND chest indrawing AND/ OR tachypnoea)
•Chest radiographs must be available for all participant categories.

•Medical instability per treating clinician’s discretion (e.g., requiring immediate resuscitation or airway support)
•Physical barriers to ultrasound (e.g bandages, chest tube, skin infection, open wound etc.)
•Patients who have been on Anti-TB treatment (ATT) during the past 6 months
•Patients on ATT for >1 week*
•Adult Pneumonia:
•Nosocomial pneumonia (onset >48 hours after admission)
•Medical instability per treating clinician’s discretion (e.g., requiring immediate resuscitation or airway support)
•Physical barriers to ultrasound (e.g bandages, chest tube, skin infection, open wound etc.)
•>24 hours since antibiotic initiation for pneumonia
•Aspiration pneumonia due to any reason.
•The inability to consent is an exclusion criteria for all adult participants.
•Paediatric TB:
•Patients who have been on ATT during the past 6 months
•Patients on ATT for >2 weeks*
•Medical instability per treating clinician’s discretion (e.g., requiring immediate resuscitation or airway support)
•Physical barriers to ultrasound (e.g bandages, chest tube, skin infection, open wound etc.)
•Paediatric Pneumonia:
•>24 hours since antibiotic initiation for pneumonia
•Medical instability per treating clinician’s discretion (e.g., requiring immediate resuscitation or airway support)
•Physical barriers to ultrasound (e.g bandages, chest tube, skin infection, open wound etc.)
•Lack of parental or guardian consent is an exclusion for both paediatric participant categories.

发起方

Gates Foundation