PHENYLEPHRINE INFUSION WITH MEPHENTERMINE INFUSION FOR MANAGEMENT OF HYPOTENSION FOLLOWING SPINAL ANAESTHESIA FOR ELECTIVE CAESAREAN DELIVERY: A COMPARATIVE STUDY
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Comparison of effect of phenylephrine and mephentermine on NIBP, SBP, DBP and HR.
研究概览
简要总结
The study aims to compare the effectiveness of phenylephrine infusion versus mephentermine infusion in managing hypotension following spinal anaesthesia during elective caeserean delivery. Key objectives include evaluating the impact of each drug on non-invasive blood pressure, Systolic blood pressure, diastolic blood pressure. The study also seeks to compare the incidence of side effects and the total number of boluses required to maintain blood pressure within 20% of baseline levels. Outcomes will be assessed at various time points during and after the procedure to determine the relative efficacy and safety of each treatment.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 21.00 Year(s) 至 40.00 Year(s)（—）
- 性别
- Female
入选标准
- •ASA 1 or 2.
排除标准
- •ASA 3 or 4 Pt. with placental complications H/o pre-eclampsia Infection at the site of SPINAL needle penetration Coagulopathies Existing neurological diseases.
结局指标
主要结局
Comparison of effect of phenylephrine and mephentermine on NIBP, SBP, DBP and HR.
时间窗: Haemodynamic parameters will be recorded- | every 2 minutes for the first 15 minutes, | then every 5 minutes till the completion of Surgery.
次要结局
- To analyse total number of boluses required to maintain BP within 20% of baseline.(Variable-as per patient requirement)
研究者
Dr Shivani Rathee
SGT Medical College