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临床试验/NCT07557706
NCT07557706招募中1 期

Using taVNS to Modulate Cardiovascular Function in Individuals With Neurologic Disease

University of Alabama at Birmingham1 个研究点 分布在 1 个国家目标入组 24 人开始时间: 2025年9月15日最近更新:

试验速览

阶段
1 期
状态
招募中
入组人数
24
试验地点
1

研究概览

简要总结

The purpose of this study is to find out whether a type of gentle nerve stimulation, called transcutaneous auricular Vagus Nerve Stimulation (taVNS), can help improve how the body regulates heart rate and blood pressure in people with Parkinson's Disease (PD). Problems with heart rate and blood pressure control are common and can make it harder for people to exercise or do daily activities. By using this non-invasive form of nerve stimulation and testing how it affects the body's natural responses, this study hopes to learn if taVNS could be a helpful tool to support physical therapy and improve overall function.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Other
盲法
Single (Participant)

入排标准

年龄范围
18 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Diagnosis of idiopathic PD
  • Stable medication for at least 4 weeks prior to the study

排除标准

  • Use of beta blockers
  • Sustained severe hypertension (>/= 180/110 mmHg while seated)
  • Significant uncontrolled cardiac arrhythmia
  • Unstable angina
  • Congestive heart failure
  • History of myocardial infarction
  • History of seizures
  • Severe cognitive impairment
  • Pregnant women or women who are planning to become pregnant

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Alexandra Evancho

Assistant Professor

University of Alabama at Birmingham

研究点 (1)

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