A Blood Biomarker for Sports-Related Brain Injury and Its Relationship With Omega-3 Status and Purposeful Soccer Heading in Free-Living Collegiate Women Soccer Players During and After a Competitive Season
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 27
- 试验地点
- 2
- 主要终点
- Change in plasma neurofilament light concentrations from baseline, during, and after a competitive season.
研究概览
简要总结
The purpose of this study is to (1) assess how a competitive season of purposeful gameplay soccer heading in collegiate women soccer players is related to a blood biomarker for sports-related brain injury, plasma neurofilament light (NF-L), and (2) examine how a player's omega-3 status is related to plasma NF-L concentration changes during and after a competitive season of gameplay soccer heading.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 25 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •At least 18 years of age.
- •Active player on the university's current team roster for the upcoming competitive season.
- •Is eligible to participate in games and is not redshirting.
排除标准
- •Is recovering from a Physician diagnosed concussion.
- •Is recovering from another injury prohibiting the study participant from participating in all sport-related activities.
结局指标
主要结局
Change in plasma neurofilament light concentrations from baseline, during, and after a competitive season.
时间窗: Baseline, 1 Months, 2 Months, 3 Months, 6 Months
Plasma neurofilament light (pg/mL) is a biomarker of axonal brain injury following sports-related head impacts.
Change in purposeful soccer heading frequencies from baseline, during, and after a competitive season.
时间窗: Baseline, 2 weeks, 4 weeks, 6 weeks, 8 weeks, 10 weeks, 12 weeks, 14 weeks
HeadCount is a web-based, structured, self-administered questionnaire to assess longer-term heading frequencies (#) during competitive play and is administered bi-weekly.
Change in Omega-3 status from baseline, during, and after a competitive season.
时间窗: Baseline, 1 Months, 2 Months, 3 Months, 6 Months
Omega-3 Index (%) is the omega-3 fatty acid content of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) within membrane of red blood cell. It is expressed as EPA+DHA as a percent of total identified fatty acids.
次要结局
未报告次要终点
研究者
Aaron Carbuhn
Assistant Professor
University of Kansas Medical Center