NL-OMON54199已完成4 期
COrticosteroids for COVID-19 induced loss of Smell - COCOS trial (AMENDMENT) - COCOS trial
适应症
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 111
研究概览
简要总结
Trial ended prematurely
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 64（—）
入选标准
- •- Infected with COVID-19, confirmed with a positive test (PCR or antigen by
- •- Persistent loss of smell after for longer than 12 weeks, (only for the
- •patients who will yet be treated with prednisolon TDI < 30.5 on Sniffin* Stick
- •test during second visit COCOS-trial )
- •- Age 18 years or older, capable of giving informed consent
- •Good understanding of the Dutch language
- •Treated with prednisolon in COCOS-trial
- •Treated with placebo in COCOS-trial
排除标准
- •Pre-existing olfactory disorders.
- •Chronic rhinitis or rhinosinusitis (with or without nasal polyps).
- •Corticosteroids use (nasal, oral or intravenously) since positive COVID test..
- •Pregnancy.
- •Contra-indications of steroid use. which contains the following:
- •-Diabetes Mellitus for which drugs (subcutaneously or orally) are used
- •-Stomach ulcers/stomachbleeding
- •-Psychoses
- •-Active oncology for which treatment is indicated
研究者
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