The Relationship Between Nocturnal Enuresis And Spina Bifida Occulta: A Prospective Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 330
- 主要终点
- Dry bed days
研究概览
简要总结
It is claimed that SBO may be responsible for bladder dysfunction in patients without known neurological disease. Subsequently, it was reported that the frequency of SBO in NE cases was higher than normal children. However, in controlled trials, SBO frequency was not different in NE patients compared to the normal population. Conversely, the incidence of dysfunctional bladder in the presence of SBO in NE patients was found to be higher and the response to treatment was worse than in non-SBO patients.
The present study aimed to determine whether the frequency of SBO in patients with NE was higher than in healthy subjects, the effect of SBO on the severity of LUTS and whether treatment response of primary NE patients changed in the presence of SBO.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 6 Years 至 15 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients aged 6 to 15 years
- •at least one night-time wetting weekly
排除标准
- •neurological disease,
- •diabetes mellitus or insipidus,
- •spinal surgery history, spina bifida skin findings,
- •chronic renal insufficiency
- •and secondary enuresis
结局指标
主要结局
Dry bed days
时间窗: 3 months
Patients were called for check-up one and three months later. When waking in the morning they were given a form to mark as dry or wet, and dry bed days were examined at check-up.
次要结局
未报告次要终点
研究者
Muhammet Fatih Kilinc
Principal Investigator
Ankara Training and Research Hospital