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临床试验/NCT04766411
NCT04766411已完成不适用

Recovery Kinetics After Different Sprint Training Protocols

University of Thessaly2 个研究点 分布在 1 个国家目标入组 10 人开始时间: 2021年3月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
10
试验地点
2
主要终点
Changes in Creatine kinase

研究概览

简要总结

Speed is one of the most important physical capacities for many sports, especially those that include speed and power as a major element, and plays a major role on performance. Running speed improvement is one of the most basic components of a sprint and power athlete's training program. One of the most commonly used strategies to improve the initial acceleration phase, is resisted sprint training. Sprinting is performed through the stretch-shortening cycle and highly includes the component of eccentric muscle contraction, which can lead to exercise induced muscle damage (EIMD). This phenomenon includes symptoms such as plasma CK elevation, delayed onset of muscle soreness, reduction in force production and a reduction in agility and speed. However, despite the fact that sprint training can cause EIMD symptoms and a performance reduction the following days, research evidence on the recovery kinetics after sprint training are scarce. However, such information is critical for coaches and athletes, in order to effectively design a training program and incorporate the training components in the training microcycle, to avoid injuries and maximize performance. The aim of the present study is to examine the recovery kinetics of EIMD indices, muscle performance and neuromuscular fatigue, after different sprint training protocols.

详细描述

Speed is one of the most important physical capacities for many sports, especially those that include speed and power as a major element, and plays a major role on performance. Thus, running speed improvement consists one of the most basic aims of a sprinter's and a power athlete's training program. One of the most commonly used strategies to improve the initial acceleration phase, is resisted sprint training. Evidence suggests that resisted sprint training is more effective in improving acceleration compared to sprint training without additional load. Sprinting is performed through the stretch-shortening cycle, where the pre-activated muscle is first stretched (eccentric action) and then followed by the shortening (concentric) action. Thus, sprint training highly includes the component of eccentric contraction. However, eccentric muscle action, especially when unaccustomed, can lead to exercise-induced muscle damage (EIMD). Although concentric and isometric exercise may also lead to muscle injury, the amount of damage after eccentric muscle contractions is greater. EIMD, amongst others, is accompanied by increased levels of creatine kinase (CK) into the circulation, increased delayed onset of muscle soreness (DOMS), reduction of force production, reduction of agility and speed. Nevertheless, despite the fact that sprint training comprises eccentric muscle actions and consequently can lead to muscle injury and muscle performance reduction during the following days, the recovery kinetics after acute sprint training have not been adequately studied. However, such information is critical for both coaches and athletes to effectively design the training microcycles and incorporate the training components, as well as to reduce injury risk.

The aim of the present study is to examine the recovery kinetics of EIMD indices, muscle performance and neuromuscular fatigue, after different sprint training protocols.

According to a preliminary power analysis (a probability error of 0.05, and a statistical power of 80%), a sample size of 8 - 10 subjects per group was considered appropriate in order to detect statistically meaningful changes between groups.

The study will be performed in a randomized, cross over, repeated measures design. During the first 1st and 2nd visit, all participants will sign an informed consent form after they will be informed about all the benefits and risks of the study and they will fill in and sign a medical history questionnaire. Fasting blood samples will be collected in order to estimate muscle damage concentration markers. Participants will be instructed by a dietitian how to record a 7-days diet recalls to ensure that they do not consume to greater extent nutrients that may affect EIMD and fatigue (e.g. antioxidants, amino acids, etc.) and to ensure that the energy intake during the trials will be the same. Assessment of body mass and body height, body composition, and aerobic capacity (VO2max), will be performed. Running speed of 10 m, 20 m and 30 m sprint will be measured on a track and field stadium. Squat jump and countermovement jump will be performed on a force platform to assess jump height, ground reaction force, peak and mean power, vertical stiffness and peak rate of force development; at the same time, peak and mean normalized EMG during the concentric phase of the squat jump, and during eccentric and concentric phases of the counter movement jump, for the vastus lateralis, biceps femoris, gastrocnemius, and gluteus maximum muscles will be assessed. The peak concentric, eccentric and isometric isokinetic torque of the knee flexors and extensors, in both limbs will be evaluated on an isokinetic dynamometer at 60°/sec. Maximal voluntary isometric contraction (MVIC) of the knee extensors at 65o in both limbs, as well as the fatigue rate during MVIC through the percent drop of peak torque between the first and the last three seconds of a 10-sec MVIC.

During the 3rd visit, participants will be randomly assigned into, and perform one of the four different conditions of the study design: a) unresisted sprint training, b) resisted sprint training with a load of 10% of body weight (BW), c) resisted sprint training with a load of 20% of BW d) control condition. Prior to each experimental protocol, assessment of DOMS in the knee flexors (KF) and extensors (KE) of both limbs, as well as blood lactate assessment will be performed. Additionally, DOMS of KF and KE, running speed at 10 m, 20 m and 30 m sprint, peak concentric, eccentric and isometric isokinetic torque, squat and countermovement jump height, as well as ground reaction force, peak and mean power, vertical stiffness and peak rate of force development during squat and countermovement jump, alongside with peak and mean normalized electromyography (EMG) during the concentric phase of the squat jump, and during eccentric and concentric phases of the counter movement jump, for the vastus lateralis, biceps femoris, gastrocnemius, and tibialis anterior muscles will be assessed immediately after, 24h, 48h and 72h after the end of the trial. MVIC of the knee extensors of both limbs, as well as the fatigue rate during MVIC will also be assessed at 1h, 2h and 3h, as well as 24h, 48h, and 72h after the end of the trial. Blood lactate will also be assessed at 4 min, while creatine kinase at 24h, 48h, and 72h after the end of the trial. The exact above procedures will be repeated by the participants during the remaining three experimental trials (7th - 10th, 11th - 13th, and 14th - 16th visits).

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Screening
盲法
None

入排标准

年龄范围
18 Years 至 30 Years(Adult)
性别
Male
接受健康志愿者

入选标准

  • Srinters or athletes that comprise sprint training in their training programs
  • Absense of musculoskeletal injuries (≥ 6 months)
  • Abstence from use of ergogenic supplements or other drugs (≥ 1 month)
  • Abstence from participation at exercise with eccentric component (≥ 3 days)
  • Abstence from alcohol and energy drings consumption before each experimental trial

排除标准

  • Musculoskeletal injuries (≤ 6 months)
  • Use of ergogenic supplements or other drugs (≤ 1 month)
  • Participation at exercise with eccentric component (≤ 3 days)
  • Alcohol and energy drings consumption before the experimental trials

结局指标

主要结局

Changes in Creatine kinase

时间窗: Baseline (pre), post-, 24 hours post-, 48 hours post-, 72 hours post-trial

CK will be measured in plasma using a Clinical Chemistry Analyzer with commercially available kits.

Changes in DOMS

时间窗: Baseline (pre), post-, 24 hours post-, 48 hours post-, 72 hours post-trial

DOMS of knee extensors and knee flexors of both lower extremities will be measured during palpation of the muscle belly and the distal regionafter performing three repetitions of a full squat.

Changes in blood lactate

时间窗: Baseline (pre), 4 minutes post-trial

Lactate will be measured in capillary blood with a hand-portable analyzer.

Changes in 10m sprint time

时间窗: Baseline (pre), 24 hours post-, 48 hours post-, 72 hours post-trial

20m sprint time will be measured using light cells Chronojump system.

Changes in mean power during squat jump

时间窗: Baseline (pre), 24 hours post-, 48 hours post-, 72 hours post-trial

Mean power during squat jump will be measured on a dynamometer using two force platforms at 1000 Hz, with each foot in parallel on the two platforms providing a separate yet time-synchronized measurement of the data for each leg.

Changes in peak rate of force development (RFD) during squat jump

时间窗: Baseline (pre), 24 hours post-, 48 hours post-, 72 hours post-trial

RFD during squat jump will be measured on a dynamometer using two force platforms at 1000 Hz, with each foot in parallel on the two platforms providing a separate yet time-synchronized measurement of the data for each leg.

Changes in peak normalized EMG during squat jump test

时间窗: Baseline (pre), 24 hours post-, 48 hours post-, 72 hours post-trial

Electromyography data will be collected wirelessly at 2000Hz using a Myon MA-320 EMG system (Myon AG, Schwarzenberg, Switzerland) for the vastus lateralis, biceps femoris, gastrocnemius, and tibialis anterior muscles during the concentric phase of the squat jump.

Changes in ground reaction force (GRF) during squat jump

时间窗: Baseline (pre), 24 hours post-, 48 hours post-, 72 hours post-trial

GRF during squat jump will be measured on a dynamometer using two force platforms at 1000 Hz, with each foot in parallel on the two platforms providing a separate yet time-synchronized measurement of the data for each leg.

Changes in vertical stiffness during squat jump

时间窗: Baseline (pre), 24 hours post-, 48 hours post-, 72 hours post-trial

Vertical stiffness during squat jump will be measured on a dynamometer using two force platforms at 1000 Hz, with each foot in parallel on the two platforms providing a separate yet time-synchronized measurement of the data for each leg.

Changes in 20m sprint time

时间窗: Baseline (pre), 24 hours post-, 48 hours post-, 72 hours post-trial

20m sprint time will be measured using light cells Chronojump system.

Changes in 30m sprint time

时间窗: Baseline (pre), 24 hours post-, 48 hours post-, 72 hours post-trial

30m sprint time will be measured using light cells Chronojump system.

Changes in squat jump height

时间窗: Baseline (pre), 24 hours post-, 48 hours post-, 72 hours post-trial

Squat jump height will be measured on a dynamometer using two force platforms at 1000 Hz, with each foot in parallel on the two platforms providing a separate yet time-synchronized measurement of the data for each leg.

Changes in peak power during squat jump

时间窗: Baseline (pre), 24 hours post-, 48 hours post-, 72 hours post-trial

Peak power during squat jump will be measured on a dynamometer using two force platforms at 1000 Hz, with each foot in parallel on the two platforms providing a separate yet time-synchronized measurement of the data for each leg.

Changes in mean normalized EMG during squat jump test.

时间窗: Baseline (pre), 24 hours post-, 48 hours post-, 72 hours post-trial

Electromyography data will be collected wirelessly at 2000Hz using a Myon MA-320 EMG system (Myon AG, Schwarzenberg, Switzerland) for the vastus lateralis, biceps femoris, gastrocnemius, and tibialis anterior muscles during the concentric phase of the squat jump.

Changes in vertical stiffness during countermovement jump

时间窗: Baseline (pre), 24 hours post-, 48 hours post-, 72 hours post-trial

Vertical stiffnesswill be measured on a dynamometer using two force platforms at 1000 Hz, with each foot in parallel on the two platforms providing a separate yet time-synchronized measurement of the data for each leg.

Changes in peak normalized EMG during countermovement jump test

时间窗: Baseline (pre), 24 hours post-, 48 hours post-, 72 hours post-trial

Electromyography data will be collected wirelessly at 2000Hz using a Myon MA-320 EMG system (Myon AG, Schwarzenberg, Switzerland) for the vastus lateralis, biceps femoris, gastrocnemius and gluteus maximum muscles during the eccentric and concentric phases of the countermovement jump test.

Changes in fatigue rate of maximal voluntary isometric contraction (MVIC)

时间窗: Baseline (pre), 1 hour post-, 2 hours post-, 3 hours post-, 24 hours post-, 48 hours post-, 72 hours post-trial

Fatigue rate during MVIC will be estimated through the percent drop of peak torque between the first and the last three seconds of a 10-second maximal isometric contaction

Changes in countermovement jump height

时间窗: Baseline (pre), 24 hours post-, 48 hours post-, 72 hours post-trial

Countermovement jump height will be measured on a dynamometer using two force platforms at 1000 Hz, with each foot in parallel on the two platforms providing a separate yet time-synchronized measurement of the data for each leg.

Changes in ground reaction force (GRF) during countermovement jump

时间窗: Baseline (pre), 24 hours post-, 48 hours post-, 72 hours post-trial

GRF will be measured on a dynamometer using two force platforms at 1000 Hz, with each foot in parallel on the two platforms providing a separate yet time-synchronized measurement of the data for each leg.

Changes in peak power during countermovement jump

时间窗: Baseline (pre), 24 hours post-, 48 hours post-, 72 hours post-trial

Peak power will be measured on a dynamometer using two force platforms at 1000 Hz, with each foot in parallel on the two platforms providing a separate yet time-synchronized measurement of the data for each leg.

Changes in mean power during countermovement jump

时间窗: Baseline (pre), 24 hours post-, 48 hours post-, 72 hours post-trial

Mean power will be measured on a dynamometer using two force platforms at 1000 Hz, with each foot in parallel on the two platforms providing a separate yet time-synchronized measurement of the data for each leg.

Changes in peak rate of force development (RFD) during countermovement jump

时间窗: Baseline (pre), 24 hours post-, 48 hours post-, 72 hours post-trial

RFD will be measured on a dynamometer using two force platforms at 1000 Hz, with each foot in parallel on the two platforms providing a separate yet time-synchronized measurement of the data for each leg.

Changes in peak concentric torque

时间窗: Baseline (pre), 24 hours post-, 48 hours post-, 72 hours post-trial

Concentric torque of knee extensors and knee flexors will be measured on an isokinetic dynamometer

Changes in mean normalized EMG during countermovement jump test

时间窗: Baseline (pre), 24 hours post-, 48 hours post-, 72 hours post-trial

Electromyography data will be collected wirelessly at 2000Hz using a Myon MA-320 EMG system (Myon AG, Schwarzenberg, Switzerland) for the vastus lateralis, biceps femoris, gastrocnemius and gluteus maximum muscles during the eccentric and concentric phases of the countermovement jump test.

Changes in peak isometric torque

时间窗: Baseline (pre), 24 hours post-, 48 hours post-, 72 hours post-trial

Concentric torque of knee extensors and knee flexors will be measured on an isokinetic dynamometer

Changes in maximal voluntary isometric contraction (MVIC)

时间窗: Baseline (pre), 1 hour post-, 2 hours post-, 3 hours post-, 24 hours post-, 48 hours post-, 72 hours post-trial

MVIC of knee extensors will be measured on an isokinetic dynamometer

Changes in peak eccentric torque

时间窗: Baseline (pre), 24 hours post-, 48 hours post-, 72 hours post-trial

Concentric torque of knee extensors and knee flexors will be measured on an isokinetic dynamometer

Change in field activity during the sprint training protocols

时间窗: Throughout the sprint training protocols

Field activity will be continuously recorded during the sprint training protocols using global positioning system (GPS) technology

Change in heart rate during the sprint training protocols

时间窗: Throughout the sprint training protocols

Heart rate will be continuously recorded during during the sprint training protocols using heart rate monitors

次要结局

  • Body mass index (BMI)(Baseline)
  • Body fat(Baseline)
  • Body height(Baseline)
  • Maximal oxygen consumption (VO2max)(Baseline)
  • Lean body mass(Baseline)
  • Dietary intake(Baseline)
  • Body weight(Baseline)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Chariklia K. Deli

Assistant Professor

University of Thessaly

研究点 (2)

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