The Effect of Different Amounts of Coffee on Dietary Intake, Appetite-related Feeling, Appetite Hormones, Glucose Metabolism and Inflammatory Markers of Normal Weight and Overweight/Obese Individuals
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 33
- 试验地点
- 1
- 主要终点
- energy intake ad libitum
研究概览
简要总结
The purpose of the study is to investigate whether different doses of caffeinated coffee consumption has acute effects on subjective appetite feelings, energy intake and biochemical markers related to appetite, inflammation and glucose metabolism compared to water consumption in normal weight and overweight/obese participants.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •apparently healthy
- •habitual coffee drinkers (>= 1cup of coffee/day)
排除标准
- •restrained eaters (as this was evaluated using the Dutch Eating Behaviour Questionnaire)
- •those who reported slimming or any other dietary regime
- •participants with a known diagnosis of either hypertension, diabetes, impaired glucose tolerance or a fasting blood glucose concentration above 125 mg/dl
- •subjects on medication for hypertension or on medication known to alter glucose metabolism
- •subjects who were on medication that may have an impact on appetite and sensory functioning or who reported a metabolic or
- •endocrine disease,
- •gastrointestinal disorders,
- •a history of medical or surgical events that may have affected the study outcomes
研究组 & 干预措施
water
干预措施: coffee (Other)
coffee6
干预措施: coffee (Other)
coffee3
干预措施: coffee (Other)
结局指标
主要结局
energy intake ad libitum
时间窗: 180 min after breakfast/drink consumption
total energy intake
时间窗: One day
appetite feelings
时间窗: 180 min after breakfast/drink consumption
appetite hormones
时间窗: 180 min after breakfast/drink consumption
markers of inflammation
时间窗: 180 min after breakfast/drink consumption
markers of glucose metabolism
时间窗: 180 min after breakfast/drink consumption
appetite feelings
时间窗: fasting (-15 min)
appetite feelings
时间窗: immediately after breakfast/drink consumption (0 min)
appetite feelings
时间窗: 15 min after breakfast/drink consumption
appetite feelings
时间窗: 30 min after breakfast/drink consumption
appetite feelings
时间窗: 60 min after breakfast/drink consumption
appetite feelings
时间窗: 90 min after breakfast/drink consumption
appetite feelings
时间窗: 120 min after breakfast/drink consumption
appetite feelings
时间窗: 150 min after breakfast/drink consumption
appetite hormones
时间窗: fasting (-15 min)
appetite hormones
时间窗: immediately after breakfast/drink consumption (0 min)
appetite hormones
时间窗: 15 min after breakfast/drink consumption
appetite hormones
时间窗: 30 min after breakfast/drink consumption
appetite hormones
时间窗: 60 min after breakfast/drink consumption
appetite hormones
时间窗: 90 min after breakfast/drink consumption
appetite hormones
时间窗: 120 min after breakfast/drink consumption
appetite hormones
时间窗: 150 min after breakfast/drink consumption
markers of inflammation
时间窗: fasting (-15 min)
markers of inflammation
时间窗: immediately after breakfast/drink consumption (0 min)
markers of inflammation
时间窗: 15 min after breakfast/drink consumption
markers of inflammation
时间窗: 30 min after breakfast/drink consumption
markers of inflammation
时间窗: 60 min after breakfast/drink consumption
markers of inflammation
时间窗: 90 min after breakfast/drink consumption
markers of inflammation
时间窗: 120 min after breakfast/drink consumption
markers of inflammation
时间窗: 150 min after breakfast/drink consumption
markers of glucose metabolism
时间窗: fasting (-15 min)
markers of glucose metabolism
时间窗: immediately after breakfast/drink consumption (0 min)
markers of glucose metabolism
时间窗: 15 min after breakfast/drink consumption
markers of glucose metabolism
时间窗: 30 min after breakfast/drink consumption
markers of glucose metabolism
时间窗: 60 min after breakfast/drink consumption
markers of glucose metabolism
时间窗: 90 min after breakfast/drink consumption
markers of glucose metabolism
时间窗: 120 min after breakfast/drink consumption
markers of glucose metabolism
时间窗: 150 min after breakfast/drink consumption
次要结局
- % carbohydrates ad libitum(180 min after breakfast/drink consumption)
- % carbohydrates total day(One day)
- % protein ad libitum(180 min after breakfast/drink consumption)
- % protein total day(One day)
- % fat(180 min after breakfast/drink consumption)
- % fat total day(One day)
研究者
M. Yannakoulia
Assistant Professor
Harokopio University