NCT05287620已完成不适用
Objective, Passive Assessment of LRRK2 Carriers
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 10
- 试验地点
- 1
- 主要终点
- Gait speed
研究概览
简要总结
The goal of this project is to identify objective, sensitive, and convenient measures for assessing early signs of Parkinson's disease in an at-risk population at home. We will do so by using a wireless sensor and analyzing the radio signals that bounce off patients' bodies, while patients go about their normal life without needing to wear sensors, answer questionnaires, or actively perform any tests.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 50 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •At least 50 years of age
- •Able and willing to provide informed consent
- •English fluency
- •U.S. resident
- •LRRK2 G2019S gene carrier, determined by participation in VALOR-PD
- •Mild parkinsonian signs, determined by modified Movement Disorder Society-Unifeid Parkinson's Disease Rating Scale (MDS-UPDRS) score from the most recent VALOR-PD visit
- •Have WiFi in their residence
- •Access to a smartphone or tablet
排除标准
- •Inability to complete study activities, as determined by the study team
- •Any medical or psychiatric condition that, in the study team's judgement, would preclude participation
- •Self-reported or VALOR-PD investigator determined Parkinson's disease
- •Any movement disorder (e.g. essential tremor)
- •Currently taking neuroleptics or other drugs known to cause parkinsonism
- •Pregnancy
- •Non-ambulatory status
- •More than one ambulatory pet in the household*
- •More than two individuals in the household (not including participant)*
- •these criteria can be waived at the discretion of the investigators
结局指标
主要结局
Gait speed
时间窗: 1 year
次要结局
未报告次要终点
研究者
Ray Dorsey
Professor
University of Rochester
研究点 (1)
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