The Effect Of Aspirin On Survival in in Patients Undergoing Chronic Hemodialysis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 410
- 主要终点
- survival rate
研究概览
简要总结
The aim of present study is to examine the effect of low-dose aspirin on the incidence of cardiovascular events and mortality in patients undergoing chronic hemodialysis.
详细描述
This study prospectively evaluate the impacts of low dose aspirin on survival and cardio-cerebral vascular events in a large cohort of Chinese patients undergoing chronic hemodialysis. Between January 2008, consecutive patients with hemodialysis with aspirin were enrolled.We examine the association of aspirin with all-cause mortality in patients matched by propensity scores using the Kaplan-Meier method and Cox models in "intention-to-treat" analyses.The secondary endpoint was rate of cardio-cerebral events.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All patients aged 18 to 85, undergoing chronic hemodialysis, who have none of the following exclusion criteria.
排除标准
- •History of gastric or duodenal ulcers Known allergy to aspirin or other NSAIDs
研究组 & 干预措施
Aspirin group
Aspirin 75-100mg,per day，oral
干预措施: acetylsalicylic acid (Drug)
结局指标
主要结局
survival rate
时间窗: 5 years
次要结局
- cardio-cerebral event(5 years)
研究者
Hui Min Jin
Shanghai Jiao Tong University School of Medicine
Shanghai Jiao Tong University School of Medicine