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临床试验/NCT07239934
NCT07239934尚未招募不适用

Diagnostic Role of Gastrointestinal Endoscopy in Assiut University Children Hospital

Assiut University1 个研究点 分布在 1 个国家目标入组 150 人开始时间: 2026年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
150
试验地点
1
主要终点
Diagnostic yield of gastrointestinal endoscopy

研究概览

简要总结

  1. To evaluate the diagnostic role, and outcomes of upper and lower gastrointestinal (GI) endoscopy in identifying gastrointestinal disorders among infants and pediatric patients attending Assiut University Children Hospital.
  2. To determine which pediatric patients require endoscopy as part of the diagnostic process.
  3. To assess the safety and effectiveness of endoscopic procedures in the detection and management of various gastrointestinal disorders among pediatric patients at Assiut University Children Hospital.

详细描述

Pediatric endoscopy plays a pivotal role in the diagnosis and management of various gastrointestinal and hepatological disorders in children.It allows doctors to see inside the digestive system, identify problems, and sometimes even treat them during the same procedure. It is a rapidly evolving field, with continuous advancements in both endoscopic technology and procedural skills, making it a safe, effective, and reliable diagnostic and therapeutic tool. Today, pediatric endoscopy is considered an essential part of evaluating and treating a wide range of gastrointestinal conditions in children. Accurate and timely diagnosis of gastrointestinal disorders is critical to prevent complications, reduce morbidity, and ensure appropriate management. These disorders are among the most common health problems affecting children worldwide. They often present with a wide variety of symptoms, including failure to thrive, unexplained anemia, recurrent vomiting, dysphagia (difficulty swallowing), acute epigastric pain, foreign body ingestion, hematemesis (vomiting blood), melena (black, tarry stools), abdominal pain, rectal bleeding, bloody diarrhea, and chronic diarrhea. At Assiut University Children Hospital, a major tertiary care center serving Upper Egypt. In recent years, there has been growing use of gastrointestinal endoscopy as a main method for diagnosing and treating various GI conditions. IT includes foreign body removal, management of caustic ingestion injuries, treatment of esophageal strictures, assessment of gastroesophageal reflux disease (GERD) severity, diagnosis of Helicobacter pylori infection through endoscopic biopsy, evaluation of eosinophilic esophagitis, management of variceal and non-variceal gastrointestinal bleeding such as deep ulcerations and gastroduodenal vascular malformations. In addition, ileocolonoscopy is commonly performed to assess lower gastrointestinal disorders such as juvenile polyps, inflammatory bowel disease (IBD), allergic colitis, vascular malformations, and infectious colitis.

研究设计

研究类型
Observational
观察模型
Other
时间视角
Prospective

入排标准

年龄范围
1 Day 至 18 Years(Child, Adult)
性别
All
接受健康志愿者

入选标准

  • Children aged from 1day to 18 years undergoing diagnostic endoscopy.

排除标准

  • Incomplete patient data.
  • Patients undergoing follow-up procedures.

结局指标

主要结局

Diagnostic yield of gastrointestinal endoscopy

时间窗: Within 30 days after endoscopy.

Proportion (%) of pediatric patients in whom gastrointestinal endoscopy provides a definitive diagnosis based on endoscopic and histopathological findings.

Distribution of clinical indications for pediatric endoscopy

时间窗: At the time of endoscopy.

Proportion (%) of children undergoing endoscopy for each indication (e.g., abdominal pain, GI bleeding, chronic diarrhea).

Correlation between clinical suspicion and confirmed diagnosis

时间窗: Within 30 days after endoscopy.

Level of agreement between pre-procedure clinical suspicion and final diagnosis based on endoscopic and histopathological findings (reported as percentage concordance).

次要结局

  • Types and frequencies of gastrointestinal disorders diagnosed by endoscopy(Within 30 days after endoscopy.)
  • Safety and complication rates of pediatric endoscopy(From the time of endoscopy until 7 days post-procedure.)
  • change in awareness among healthcare providers(Up to 6 months from start of study.)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Aml Shaban Mohamed Farghly

Resident of Pediatrics, Assiut University Children's Hospital

Assiut University

研究点 (1)

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