Development of a Mass-spectometry Based Method for Detecting Xenon Application in Humans
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 8
- 试验地点
- 1
- 主要终点
- Detection of xenon in patient blood sample by mass spectrometry
研究概览
简要总结
The purpose of this study is to establish a laboratory method to determine from blood samples whether a person has been treated with xenon.
详细描述
The noble gas xenon is used for general anesthesia in clinical routine. Recent reports indicate that xenon is also used for increasing performance in high-performance sports. The purpose of this study is to establish a method for detecting xenon exposure in humans.
In patients undergoing surgery with xenon anesthesia as part of routine hospital care, small blood samples (3ml) will be taken before anesthesia, during anaesthesia and at 1,2, 4, 8, 16, 24, 32, 40 and 48 hours after anesthesia. These blood samples will be analyzed for traces of xenon.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age of 18 years and older
- •Xenon-based anesthesia as part of routine care
排除标准
- •Inability to give written informed consent
- •Known pregnancy
- •Hemoglobin concentration of less than 12g/dl
研究组 & 干预措施
Xenon
Patients undergoing surgery with xenon-based general anesthesia
干预措施: Anesthesia with inhalative application of xenon gas (Drug)
结局指标
主要结局
Detection of xenon in patient blood sample by mass spectrometry
时间窗: 24 hours after xenon anesthesia
次要结局
未报告次要终点
研究者
Klinik für Anästhesiologie
Prof. Dr. Peter Kienbaum
Heinrich-Heine University, Duesseldorf