NCT07167511已完成不适用
Efficacy and Safety of Bismuth-containing Quadruple Therapy for First Line Helicobacter Pylori Eradication: A Multicenter Retrospective Study
Yueyue Li1 个研究点 分布在 1 个国家目标入组 1,730 人开始时间: 2022年1月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 1,730
- 试验地点
- 1
- 主要终点
- Eradication rate
研究概览
简要总结
Bismuth-containing quadruple therapy was recommended as a first-line treatment for Helicobacter pylori infection. This study aimed to compare real-world outcomes of various bismuth-containging quadruple regimens and identify factors influencing treatment failure. A multicenter retrospective analysis was conducted and study outcomes included eradication rates and incidence of adverse events.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients aged 18-70 years, regardless of gender;
- •absent history of receiving H. pylori eradication therapy;
- •diagnosed with H. pylori infection through at least one of the following methods: rapid urease test, ¹³C/¹⁴C-urea breath test, or histopathological examination.
排除标准
- •patients with incomplete medical records, including missing treatment details, absence of post-treatment follow-up test results, or failure to complete essential follow-up assessments;
- •patients who received treatment regimens that did not comply with the quadruple regimens specified in this study.
结局指标
主要结局
Eradication rate
时间窗: 6 weeks after treatment completion
Comparison of eradication rates among quadruple therapies for Helicobacter pylori
次要结局
- Adverse events(Immediately after treatment completion)
研究者
Yueyue Li
Associate Professor
Qilu Hospital of Shandong University
研究点 (1)
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