Walking Program in Fatty Liver Children With Phenylketonuria: Response of Liver Enzymes
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- alanine transamianse
研究概览
简要总结
phenylketonuria (commonly known as PKU) is an inherited disorder that increases the levels of a substance called phenylalanine in the blood. PKU is usually associated with many metabolic complication including non-alcoholic fatty liver
详细描述
this study will include PKU children sufferers 9n=40) with non-alcoholic fatty liver to be randomly assigned to group I (n=20) that will perform walking program (online supervised free walking that will be applied daily for eight weeks) or group II (N=20) that will act as waitlisted children
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 9 Years 至 12 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •PKU children
- •obese children
- •fatty liver children (non-alcoholic fatty liver)
排除标准
- •cardiac children
- •diabetic children
- •neurogenic disorders
- •respiratory and renal problems
研究组 & 干预措施
group I
this Group I will include PKU children sufferers (n=20) with non-alcoholic fatty liver that will perform walking program (online supervised free walking that will be applied daily for eight weeks)
干预措施: walking free online supervised program (Behavioral)
Group II
this Group II will include PKU children sufferers (n=20) with non-alcoholic fatty liver that will act a waitlisted children
结局指标
主要结局
alanine transamianse
时间窗: it will be assessed after eight weeks
it is a serum liver enzyme
次要结局
- aspartate tranaminase(it will be assessed after eight weeks)
- Gamma-glutamyl Transferase(it will be assessed after eight weeks)
- alkaline phosphatase(it will be assessed after eight weeks)
- triglycerides(it will be assessed after eight weeks)
- body mass index(it will be assessed after eight weeks)
研究者
Ali Mohamed Ali ismail
Department of Physical Therapy for Cardiovascular/Respiratory Disorder and Geriatrics, Faculty of Physical Therapy
Cairo University