跳至主要内容
临床试验/NCT02666937
NCT02666937已完成不适用

Safe Limits in Saturation (SLIM-study)

Amsterdam UMC, location VUmc1 个研究点 分布在 1 个国家目标入组 879 人开始时间: 2015年12月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
879
试验地点
1
主要终点
Relation SpO2-PaO2

研究概览

简要总结

A study consisting of a prospective and retrospective cohort in the ICU, ER and pulmonary department in a university hospital in Amsterdam and a teaching hospital in Alkmaar, the Netherlands.

The relationship between the oxygen saturation measured by pulse-oximetry and the arterial PaO2 is investigated in order to investigate which transcutaneous saturation values are safe when administering oxygen in relation to hyperopia and hypoxia.

详细描述

This study consists of two parts a prospective and a retrospective part.

  1. Prospective part: Patients in the ICU, the emergency room and the pulmonary function department of the VU university medical centre will be included. Arterial blood gas analysis is a tool often used to determine PaO2 in regular care. When an arterial blood gas analysis is performed for regular patient care, the corresponding SpO2 is measured. Information such as blood pressure, heart rate, amount of administered fluids and shock-related-parameters are obtained from the patient files. For the ICU patients capillary refill, acra temperature and the mottling scores are examined. The peripheral flow index and temperature index is measured. When more arterial blood gas samples are drawn over time in one patient, multiple datasets can be included per patient, as long as the samples are drawn two hours apart.
  2. Retrospective part: Patients with a (suspected) pulmonary disease who underwent pulmonary function tests with arterial bloodgas sampling in the VU medical center and Medical Centre Alkmaar in the last 25 years. The PaO2 and corresponding SpO2 will be obtained from the test and parameters such as blood pressure, heart rate and administered oxygen will be retrieved from the databases with these test results.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Other

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • 未提供

排除标准

  • 未提供

结局指标

主要结局

Relation SpO2-PaO2

时间窗: Average of one week

To determine peripherally measured saturation targets between which no hyperoxia and hypoxia will occur

次要结局

  • Factors influencing PaO2-Spo2 relation(Average of one week)
  • Relation in SpO2-PaO2 in different populations(Average of one week)
  • Differences in relation in SpO2-PaO2 prospective versus retrospective(Average of one week)

研究者

发起方
Amsterdam UMC, location VUmc
申办方类型
Other
责任方
Principal Investigator
主要研究者

Angelique Spoelstra-de Man

Dr. A.M.E. Spoelstra--de Man

Amsterdam UMC, location VUmc

研究点 (1)

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