NCT05224596Unknown不适用
Gastric Cancer Detection by Liquid Biopsy in Peripheral Blood: A Prospective Study
Shanghai Zhongshan Hospital1 个研究点 分布在 1 个国家目标入组 498 人开始时间: 2021年1月18日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 498
- 试验地点
- 1
- 主要终点
- Sensitivity and specificity of the cfDNA methylation-based model in detecting gastric cancer.
研究概览
简要总结
ASCEND-Gastric is a prospective, multi-omics, observational study aimed at detecting gastric cancer by combined assays for serum protein markers, deep sequencing of cell-free DNA (cfDNA), circulating tumor DNA (ctDNA) mutation and circulating RNA. The study will enroll 498 participants, including 128 patients with benign gastric diseases and 370 patients with gastric cancer.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 40 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Sensitivity and specificity of the cfDNA methylation-based model in detecting gastric cancer.
时间窗: 30 months
次要结局
- Sensitivity and specificity for detecting gastric cancer of a cfDNA methylation-based model, in combination with other biomarkers.(30 months)
- The differences of sensitivity and specificity in gastric cancer participants at different clinical stages.(30 months)
- Sensitivity and specificity of a ctDNA mutation-based model and a serum protein-based model in detecting gastric cancer, respectively.(30 months)
研究者
研究点 (1)
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