eural plasticity in a Virtual reality-Treadmill combined Intervention for enhancing Mobility and reducing falls in Elderly (V-TIME) with Parkinson's Disease - V-TIME neural plasticity study

niversitair Medisch Centrum Sint Radboud0 个研究点目标入组 70 人开始时间: 待定最近更新: 2024年4月29日

适应症

试验速览

暂无简介。

•Patients are eligible for participation if they meet all of the following inclusion criteria:
•- >=2 falls within the 6 months prior to the study
•- Age range: 60-85 years
•- Diagnosis of PD (UKBB criteria)
•- Hoehn and Yahr stage II-III (on medication)
•- Stable medication for at least one month and anticipated for the next 6 months
•- Able to walk at least 5 minutes unassisted
•- Adequate hearing and vision

•Patients will be excluded from the study if they meet any of the following criteria:
•- Psychiatric co-morbidities (e.g., major depression - DSM IV criteria)
•- Clinical diagnosis of dementia (e.g., Alzheimer*s, vascular, etc.)
•- History of stroke, traumatic brain injury, brain tumour or other neurological disorders
•- Acute lower back or lower extremity pain, musculoskeletal injuries, peripheral neuropathy which restricts gait
•- Unstable medical condition including cardiovascular instability in past 6 months
•- Unable to comply with training
•- Cognitively impaired (< 24 on Mini-Mental State Examination)
•- Interfering therapy, or fall clinic visit <1 month ago
•- Severe freezing precluding safe participation (>15 on New Freezing of Gait Questionnaire)
•- Metal objects or fragments in/on body
•- Active implant (e.g. pacemaker, neurostimulator, insulin pump)
•- Epilepsy
•- Claustrophobia

发起方

niversitair Medisch Centrum Sint Radboud