ISRCTN84197855已完成未知
The effect of dietary nitrate supplementation on dynamic cerebral autoregulation in ischaemic stroke: a pilot randomised controlled trial
South Devon Healthcare NHS Foundation Trust (UK)0 个研究点目标入组 16 人开始时间: 2014年6月6日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 16
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Subjects must have a confirmed onset of acute ischaemic stroke within the last 14 days
- •2. Age 18-90
- •3. Able to lie supine and still for 30 minutes
- •4. Able to take liquid orally
- •5. Able to give full informed consent
- •6. Adequate temporal acoustic window as assessed with transcranial doppler ultrasound
排除标准
- •1. Stroke onset within 24 hours
- •2. Haemorrhagic stroke
- •3. Pregnant women
- •4. Dysphagia precluding oral intake of liquid
- •5. Inadequate temporal acoustic window for transcranial ultrasound
- •6. Exclude vasoactive drugs including calcium channel blockers
- •7. Regularly taking organic nitrates, nicorandil, glitazones, phosphodiesterase inhibitors
- •8. Pre-existing dementia
- •9. Significant carotid stenosis >70% on carotid doppler
- •10. Severe peripheral vascular disease
研究者
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