JPRN-UMIN000042181已完成未知
Cognitive decline and brain structural alterations caused by metabolic dysfunction in older adults with type 2 diabetes: a prospective observational study. - Cognitive decline and brain structural alterations caused by metabolic dysfunction in older adults with type 2 diabetes: a prospective observational study.
Center for Comprehensive Care and Research on Memory Disorders, National Center for Geriatrics and Gerontology.0 个研究点目标入组 100 人开始时间: 2020年10月26日最近更新:
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 100
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 70years-old 至 86years-old（—）
- 性别
- All
入选标准
- 未提供
排除标准
- •Subjects who 1) are diagnosed with type 1 diabetes mellitus. 2) are diagnosed with dementia. 3) are unable to perform cognitive tests. 4) use implanted medical devices, such as pacemakers. 5) decreased cognitive function due to Parkinson's disease, apoplexy, Huntington's disease, normal pressure hydrocephalus, brain tumors, progressive supranuclear palsy, corticobasal degeneration, multiple system atrophy, aphasia, epilepsy, subdural hematoma, encephalitis/meningitis, multiple sclerosis, or head injury. 6) have any local lesion, such as cerebral infarction(s) detected by CT or MRI before enrollment, that may greatly affect cognitive function. 7) have a history of major depression, bipolar disorder, schizophrenia, or alcohol/drug abuse; have current serious or unstable disease. 8) unsuitable for treatment due to vitamin B1/B12 and/or folate deficiency, or thyroid dysfunction 9) are deemed ineligible for enrollment by the responsible researcher or co-researcher.
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