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临床试验/NCT04344119
NCT04344119招募中不适用

Assessment of Skin Manifestations Occuring During Covid-19 Infection With a Special Focus on Chilbains

Centre Hospitalier Universitaire de Nice1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2020年4月9日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
30
试验地点
1
主要终点
Clinical skin manifestations

研究概览

简要总结

Some patients infected by covid-19 develop skin manifestations. These manifestations are still not well known and there pathophysiology remain unclear. Among them, acral manifestation resembling to chilblains appears frequent and quite specific. The aim of this project is to better characterize the cutaneous manifestations occurring during Covid-19 infection with a special focus on chilblains. These acral manifestation could be due to a direct viral effect, but also to microthrombosis or vascularitis. Understanding the pathomechanisms involved could provide interesting clue for understanding not only the skin manifestations but also some of the other systemic symptoms associated to covid-19 infection. This study plan to characterize these acral manifestations by analyzing the clinical and dermoscopic patterns and to correlate them with the non-invasive vascular explorations but also immune and coagulopathy explorations that are done in the CHU of Nice in covid-19 patients.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Prospective

入排标准

年龄范围
— 至 90 Years(Child, Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • All patients with proven covid infection (using PCR, serum antibody or lung TDM) and presenting at least one cutaneous lesions that occurred during the infection.

排除标准

  • 未提供

结局指标

主要结局

Clinical skin manifestations

时间窗: 3 months

Type and description of the skin manifestations with a special focus on patients with chilblains

次要结局

  • Histology and biological data(3 months)
  • Non invasive vascular examination(3 months)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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