A Randomized Controlled Trial on the Effectiveness of Cissus quadrangularis (Pirandai) Topical Gel for Managing Arthritis-Related Bone
试验速览
- 阶段
- 2/3 期
- 状态
- 尚未招募
- 入组人数
- 93
- 试验地点
- 1
- 主要终点
- Reduction in pain scores using the Visual Analogue Scale (VAS) at baseline, 2 weeks, and 4 weeks.
研究概览
简要总结
14. Objectives of the project :
- To evaluate the effectiveness of Cissus quadrangularis (Pirandai) topical gel in reducing arthritis-related bone pain compared to a placebo among adult patients
- To evaluate the safety and tolerability of Cissus quadrangularis topical gel in the study population
15. Expected duration of the project : 1 year
16. Benefit of the research project :
This study evaluates the effectiveness of a Cissus quadrangularis (Pirandai) herbal infusion formulated as a topical gel, aiming to offer a scientifically validated, plant-based therapeutic option within the framework of modern medicine. By integrating traditional knowledge with clinical evidence, the research has the potential to introduce a safe, accessible, and locally available remedy into mainstream arthritis care—especially valuable in settings where long-term pharmacological treatment may be costly or associated with adverse effects
16.1 To the Participants/patients :
Participants may experience relief from arthritis-related bone pain through the application of a natural, non-invasive topical gel.The study promotes awareness of scientifically supported herbal interventions that can complement conventional treatment strategies.Reduced dependence on long-term use of oral analgesics or NSAIDs, potentially minimizing associated side effects
16.2 To the Society/Knowledge :
Contributes to the scientific integration of traditional herbal remedies into modern, evidence-based medical practice.Promotes the use of cost-effective and accessible alternatives for managing chronic joint pain, particularly in resource-limited settings.
Encourages interdisciplinary collaboration between traditional medicine and clinical research.Informs public health initiatives by introducing validated herbal options that can complement standard arthritis care and reduce reliance on long-term pharmacological treatments
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 40.00 Year(s) 至 75.00 Year(s)（—）
- 性别
- All
入选标准
- •Adults more than 40 years of age Diagnosed with Arthitis for more than 3 months Willingness to participate with informed consent.
排除标准
- •Should not be on Oral corticosteriod tropical and intramuscuoar corticosteriods respectively.
结局指标
主要结局
Reduction in pain scores using the Visual Analogue Scale (VAS) at baseline, 2 weeks, and 4 weeks.
时间窗: Every 2nd weeks, and 4 th weeks For three months
次要结局
- Change in joint function assessed by WOMAC score(Patient reported improvement & satisfaction)
研究者
Dr Ragasrimathi R G
Saveetha medical College and hospital