Comprehensive Assessment of Subclinical Atherosclerosis in Patients With Rheumatoid Arthritis
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 100
- 主要终点
- Cardiovascular disease risks in patient with theumatoid arthritis
研究概览
简要总结
Cardiovascular disease is a leading cause for morbidity and mortality in general population. The incidence of cardiovascular disease and their poor outcome is well documented in a broad spectrum of connective tissue diseases, especially in rheumatoid arthritis (RA). The risk of incident CVD is increased by 48% in patients with RA compared to the general population.
RA is associated with 50% increase in the mortality in patients with cardiovascular disease (CVD). One reason is the more frequent cardiovascular risk factors in RA patients compared with the general population. Patients with RA have a high risk of premature cardiovascular disease (CVD). The aim of the present study is to assess whether there are non-invasive measures that might predict arteriosclerosis in RA patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •18-70 years old (except for women till 75 years old)
- •Absence of established CVD:
- •Myocardial Infarction p/h
- •PCI with balloon and/or stent
- •Intermittent claudication
- •PAD / intervention
- •CAS /intervention
- •Signed informed consent form
- •Documented diagnosis of rheumatoid arthritis
排除标准
- 未提供
结局指标
主要结局
Cardiovascular disease risks in patient with theumatoid arthritis
时间窗: 6 months
Prediction of cardiovascular risks and proposed preventive treatment
次要结局
未报告次要终点
研究者
Osamah Hussein
Head of Internal Medicine A
Ziv Hospital