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临床试验/NCT06267443
NCT06267443Unknown不适用

Comparison of Two Different Techniques for Postoperative Analgesia in Cardiopulmonary Bypass Surgeries: Erector Spinae Plane Block or Parasternal Block Plus Chest Tube Wound Infiltration

TC Erciyes University0 个研究点目标入组 100 人开始时间: 2024年3月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
入组人数
100
主要终点
postoperative analgesia

研究概览

简要总结

Pain management is important after coronary artery bypass graft (CABG) surgery. Intravenous morphine is the gold standard for pain relief, but its sedation, cough suppression and decreased bowel movements limit its use. Analgesia with regional methods after surgery provides effective analgesia by reducing morphine consumption. In this study we have planned to compare the erector spina plane block with parasternal block +local infiltration to chest tube areas.

详细描述

Patients who will undergo open heart surgery will be included in this study. Pain management is important after coronary artery bypass graft (CABG) surgery. Poorly controlled postoperative pain can trigger myocardial ischemia, increase catecholamine levels, result in increased complications such as stroke and bleeding, and increase the risk of pneumonia. Intravenous morphine is the gold standard for pain relief, but its sedation, cough suppression and decreased bowel movements limit its use. For this reason, regional methods are gaining importance in pain treatment. After cardiac surgery. Both sternotomy and bilateral chest tubes are the most painful interventions during cardiac surgeries. Parasternal block can be a good alternative in the treatment of pain in CABG surgeries. In parasternal application, the aim is to anesthetize the nerves innervating the sternum between the pectoral muscle and the intercostal muscle by holding the probe in the parasagittal plane on the lateral side of the sternum under USG guidance. Patients who will undergo open heart surgery will be included in this study. The patients will be divided into two groups, and in Group 1, before general anesthesia is given, bilateral ESPB will be performed at the 4-6th thoracic level in the prone position, and then routine general anesthesia will be performed (at this stage, the patients will be given sedation to prevent them from feeling pain). After endotracheal intubation, in Group 2, a parasternal block will be performed from the lateral sternum. At the end of the surgery, local anesthetic infiltration will be perform to the tube sites. General anesthesia and surgical procedures will be performed routinely in both groups. In the intensive care unit patients will be monitored for pain levels, intubation duration, whether there is atelectasis in the lungs, and the need for reintubation. Pain assessment will be evaluated with the behavioral pain score while the patients are intubated and with the visual pain scale after extubation. Whether atelectasis has developed will be evaluated with ultrasonography at the 12th and 24th hours postoperatively

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Single (Participant)

入排标准

年龄范围
18 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者
否

入选标准

  • •Patients who will undergo open heart surgery
  • •Patients who agreed to participate in the study-

排除标准

  • •Patients who do not agree to participate in the study
  • •Patients with chronic lung disease
  • •Patients with D. Mellitus

研究组 & 干预措施

Group 2

Active Comparator

in this group after endotracheal intubation bilateral parasternal block will be performed and to the chest tube sides local anesthetic infiltration will be performed

干预措施: Comparison of erector spina plane block, parasternal block plus local infiltration to the tube sides for postoperative analgesia (Procedure)

Group 1

Active Comparator

in this group erector spina plane block will be performed before surgery for post operative analgesia

干预措施: Comparison of erector spina plane block, parasternal block plus local infiltration to the tube sides for postoperative analgesia (Procedure)

结局指标

主要结局

postoperative analgesia

时间窗: 24 hours after after surgery

postoperatively in the intensive care unit during mechanical ventilation behavioral pain, score, after extubation visüel analog scala will be used to measure postoperative pain of the patients. during mechanical ventilation every 2 hours after extübation 2., 4., 6., 8., 12., 24. hours

postoperative atelectasia

时间窗: 24 hours after after surgery

postoperatively at the 12. th and 24.th hours with ultrasonography the patients lungs will be sreened for atelectasis

次要结局

  • postoperative mechanical ventilation duration(24 hours after after surgery)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Ayse Ulgey

PROFESSOR DR

TC Erciyes University

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