MRI Exploration of Meningeal Inflammatory Disease
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 302
- 试验地点
- 1
- 主要终点
- detection of meningeal contrast enhancement with the FABIR sequence
研究概览
简要总结
Patients who have agreed to participate in the study will complete the MRI protocol as part of routine care, to which two additional sequences of 6 minutes duration will be added.
The MRI of routine care includes at least the following sequences:
- 3D T1 TFE 1.0 isotropic (2 minutes)
- T2 TSE (2 minutes)
- 3D FLAIR pre-injection (opt) (3 minutes)
- 3D FLAIR post-injection (3 minutes)
As part of the research, the following sequences will be acquired:
- FABIR pre-injection (3 minutes)
- FABIR post-injection (3 minutes)
Patients hospitalized for a foreseeable duration of at least 24 hours will be offered participation in the longitudinal tab of the study, for which four non-injected MRI examinations will be performed. The examinations will be carried out remotely from the injected MRI (1h, 2h, 12h-15h, 24h-36h). These exams dedicated to research will include the following sequences for a maximum of 8 minutes:
- 3D T1 TFE 1.0 isotropic (2 minutes)
- 3D FLAIR (3 minutes)
- FABIR (3 minutes)
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient over 18 years old
- •To benefit as part of his treatment of an MRI with injection of gadolinium
- •Express consent to participate in the study
- •Affiliate or beneficiary of a social security scheme
- •For the ancillary study to meet secondary endpoint number 5:
- •Patient over 18 years old
- •To benefit as part of his treatment of an MRI with injection of gadolinium
- •Hospitalized for an expected period of at least 48 hours after the time of inclusion
- •Express consent to participate in the study
- •Affiliate or beneficiary of a social security scheme
排除标准
- •Patient benefiting from a legal protection measure
- •Pregnant or breastfeeding woman
结局指标
主要结局
detection of meningeal contrast enhancement with the FABIR sequence
时间窗: 1 day
detection of meningeal contrast enhancement with the flair sequence
时间窗: 1 DAY
次要结局
未报告次要终点