跳至主要内容
临床试验/NCT06775574
NCT06775574已完成不适用

Prognostic Significance of the Lung Immune Prognostic Index (LIPI) in Postoperative Clear Cell Renal Cell Carcinoma: a Multicenter Retrospective Cohort Study

Wuhan Union Hospital, China1 个研究点 分布在 1 个国家目标入组 704 人开始时间: 2014年11月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
704
试验地点
1
主要终点
overall survival (OS)

研究概览

简要总结

This retrospective study included 704 patients with ccRCC who underwent radical or partial nephrectomy. Patients were stratified into the LIPI good group and the intermediate/poor (int./poor) group based on dNLR (≥ 3) and LDH (≥ 245 U/L) levels. Propensity score matching (PSM) was used to adjust for baseline differences and minimize selection bias. Kaplan-Meier survival curves and Cox regression models were employed to evaluate the impact of LIPI and other clinical factors on recurrence-free survival (RFS) and overall survival (OS).

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

性别
All
接受健康志愿者

入选标准

  • Pathologically diagnosed with ccRCC;
  • Underwent radical or partial nephrectomy.

排除标准

  • presence of concurrent malignancies;
  • missing data or failure to follow-up

结局指标

主要结局

overall survival (OS)

时间窗: 5 years

recurrence-free survival (RFS)

时间窗: 5 years

次要结局

未报告次要终点

研究者

发起方
Wuhan Union Hospital, China
申办方类型
Other
责任方
Sponsor

研究点 (1)

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