Systems Biology of Gastrointestinal and Related Diseases
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 发起方
- 入组人数
- 17
- 试验地点
- 1
- 主要终点
- Identification of human determinants of gastrointestinal diseases.
研究概览
简要总结
This is a longitudinal observational study on patients with gastrointestinal and related disease. The study will be conducted for at least 10 years, following each participant over time, as they either go through relapses and remissions, or progression of their disease.
详细描述
This is a longitudinal, observational study whose main goal is to identify the human and microbial determinants of gastrointestinal diseases. Molecular and metadata will be collected from a large study population at multiple time points. Machine learning will be applied to all data, and models will be evaluated for development of novel diagnostic and therapeutic tools.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Identification of human determinants of gastrointestinal diseases.
时间窗: Up to 10 years
Identification of biomarkers that indicate gastrointestinal diseases.
Identification of microbial determinants of gastrointestinal diseases.
时间窗: Up to 10 years
Identification of microbial species that indicate gastrointestinal disease.
次要结局
- Quantify change in microbial species over time post colonoscopy(Up to 10 years.)
- Prediction of efficacy of biologics in treating IBD.(Up to 10 years.)
- Development of a molecular test for C. difficile infection (CDI)(Up to 10 years.)