Conduct of Anaesthesia During Acute Ischaemia Stroke: a Retrospective Case Series of Patients Undergoing Mechanical Thrombectomy
试验速览
- 阶段
- 不适用
- 入组人数
- 250
- 主要终点
- Evaluating the number of patients requiring mechanical thrombectomy
研究概览
简要总结
Title: Conduct of anaesthesia during acute ischaemic stroke: a retrospective case series of patients undergoing mechanical thrombectomy.
Design: This study will be a retrospective consecutive observational case series
详细描述
The Aim of this study is to describe the baseline characteristics, procedural and post-operative clinical characteristics of anaesthetic care delivered to consecutive adult patients who underwent mechanical thrombectomy as part of their routine clinical care between 01/01/2016 and 01/10/2020 at Nottingham University Hospitals NHS Trust (sample size approximately 250).
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age ≥ 18 years old
- •Undergone mechanical thrombectomy for the management of acute ischaemia stroke between 01/01/2016-01/10/2020 at Nottingham University Hospitals NHS Trust.
排除标准
- •No pre-specified exclusion criteria.
结局指标
主要结局
Evaluating the number of patients requiring mechanical thrombectomy
时间窗: Through study completion, up to 9 months
This retrospective study will identify the anaesthetic care delivered to a group of patients undergoing mechanical thrombectomy for the management of acute ischaemic stroke. The data collected will be from all patients that received this treatment between 01/01/2016 and 01/10/2020 at Nottingham University Hospitals NHS Trust. This data written up and of interest both to our organisation and to comparable neuroscience centres in the UK and internationally. Outcomes that will be measured in this clinical case study are highlighted below.
次要结局
- Background information: Age (>/= 18 years of age)(Through study completion, up to 9 months)
- Background information: Gender (male or female)(Through study completion, up to 9 months)
- Background information: The degree of disability/dependence after a stroke will be measured using the presenting modified Rankin Score(Through study completion, up to 9 months)
- Background information: Presenting blood pressure (systolic and diastolic)(Through study completion, up to 9 months)
- Background information: Presenting heart rate (beats per minute)(Through study completion, up to 9 months)
- Background information: The fitness of the patient will be measured using the American Society of Anaesthetists Classification(Through study completion, up to 9 months)
- Background information: Height of the patient (m)(Through study completion, up to 9 months)
- Background information: Weight of the patient (kg)(Through study completion, up to 9 months)
- Background information: Measuring the distance from referring hospital (miles)(Through study completion, up to 9 months)
- The patient's stroke classification will be measured using National Institute for Health Stroke Scale(Through study completion, up to 9 months)
- Mode of anaesthesia(Through study completion, up to 9 months)
- To identify the anaesthetic agents used(Through study completion, up to 9 months)
- The level of the anaesthetist (registrar / consultant)(Through study completion, up to 9 months)
- Intra - procedural observations: Measuring time spent with systolic blood pressure (mmHg) <10% of presenting BP (minutes)(Through study completion, up to 9 months)
- Intra - procedural observations: Quantifying any episodes of hypoxia (SpO2 <94%)(Through study completion, up to 9 months)
- Intra-procedural interventions: Identifying if the patient required vasopressors(Through study completion, up to 9 months)
- Measuring the response of treatment using the post-procedural Thrombolysis in Cerebral Infarction scale(Through study completion, up to 9 months)
- To identify the level of care required immediately post procedure (Level 0,1,2,3)(Through study completion, up to 9 months)
- Identify the duration of Intensive Care stays (days)(Through study completion, up to 9 months)
- Identify the duration of stay in hospital (days)(Through study completion, up to 9 months)
- To measure the long term outcome: National Institute for Health Stroke Scale at 24 hours post-procedure(Through study completion, up to 9 months)
- To measure the long term outcome: Modified Rankin Score at 90 days(Through study completion, up to 9 months)
- To measure the long term outcome: Mortality at 90 days (survived / deceased)(Through study completion, up to 9 months)
- To measure the long term outcome: Discharge destination (home / institution)(Through study completion, up to 9 months)