PACTR201512001370307招募中未知
Randomised placebo-controlled trial of oral doxycycline to reduce recurrent trachomatous trichiasis
ondon School of Hygiene & Tropical Medicine0 个研究点目标入组 1,000 人开始时间: 2015年11月29日最近更新:
试验速览
- 阶段
- 未知
- 状态
- 招募中
- 发起方
- 入组人数
- 1,000
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 Year(s) 至 100 Year(s)（—）
- 性别
- All
入选标准
- •1.Trachomatous Trichiasis with tarsal conjunctival scarring
- •2.Adults (>18 years of age)
- •3.Agree to be randomly allocated to receive doxycycline or placebo following surgery
- •4.Agree to re-examination at one week, one, six and twelve months after surgery
排除标准
- •1.Age less than 18 years
- •2.Pregnant or breast-feeding women
- •3.Previous eyelid surgery
- •4.Medically unfit, BP systolic >170, diastolic >110
- •5.People with known history of hypersensitivity/allergy to Doxycycline or Tetracycline
- •6.Presence of contra-indication to doxycycline usage
- •oTaking warfarin
- •oTaking sulphonylurea based medication for diabetes
- •oPre-existing known liver or renal impairment
- •oMyasthenia gravis
- •7.Patients with trichiasis from other eyelid pathologies, such as:
- •oBlepharitis
- •oSteven Johnson syndrome
- •oEyelid muscle laxity due to aging
- •oHerpes zoster
- •oOcular cicatricial pemphigoid
研究者
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