Study on effect of topiroxostat administration on serum creatinine level in patients with hyperuricemia. - Study on effect of topiroxostat administration on serum creatinine level in patients with hyperuricemia.

Koto Hospital0 个研究点目标入组 104 人开始时间: 2020年1月10日最近更新: 2023年10月17日

适应症

试验速览

阶段: 未知
状态: 已完成
发起方
入组人数: 104

研究概览入排标准研究者记录与标识符相似试验

研究概览

简要总结

After 12 months, sUA significantly decreased, but. sCr and eGFR showed slightly non-significant changes from the baseline. sCr were significantly increased during 6 months before topiroxostat administration (p < 0.001) but showed no significant change at 6 months after topiroxostat treatment (p = 0.682).

研究设计

研究类型: Observational

入排标准

年龄范围: 20years-old 至 ot applicable（—）
性别: All

入选标准

未提供

排除标准

•(1) Patient has serious liver or kidney disease at initiation of topiroxostat treatment (2) Patient undergoing hemodialysis or has undergone kidney transplantation at initiation of topiroxostat treatment (3) Patient has comorbid malignancy at initiation of topiroxostat treatment (4) Patient coadministered another urate-lowering drug at initiation of topiroxostat treatment (5) Patient deemed unsuitable for participation in this research by the investigator

研究者

发起方

Koto Hospital

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