跳至主要内容
临床试验/NCT00219505
NCT00219505终止不适用

Effect of Acupuncture on Symptoms of Diarrhea and Pain in Diarrhea Predominant Irritable Bowel Syndrome (IBS) and Effect on Plasma Beta-endorphin and Serotonin Levels.

Penn State University2 个研究点 分布在 1 个国家目标入组 36 人开始时间: 2001年8月最近更新:
适应症

试验速览

阶段
不适用
状态
终止
入组人数
36
试验地点
2
主要终点
Frequency of bowel movement

研究概览

简要总结

Acupuncture has been used for centuries in China in the treatment of diarrhea. Our hypothesis is that acupuncture is effective in the treatment of abdominal pain and diarrhea in patients with diarrhea-predominant IBS

详细描述

Patients will complete a diary to determine if they qualify for the study. Patients will be randomized to receive either acupuncture or sham acupuncture (needle insertion 1 cm away from acupuncture site). Patients will be blinded to whether they are receiving acupuncture or sham acupuncture. The acupuncturist is blinded as to the patient response. The patients will undergo venupuncture to draw blood to determine sertotonin and beta-endorphin levels. They will receive treatment in 12 sessions over 4 weeks. They will maintain a diary during this time period to document level of pain and frequency of bowel movements. Blood will be drawn at week 2 and 4 and, 6 weeks after cessation of treatment, subjects will again record abdominal symptoms and frequency of bowel movements for 2 weeks. Blood will be drawn for hormone levels at 8 weeks after completion of study.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Factorial
主要目的
Treatment
盲法
Single

入排标准

年龄范围
18 Years 至 90 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • frequence of bowel movement of at least 3/day
  • global disease severity of at least 3

排除标准

  • taking medications which will influence frequency of bowel movement
  • patient taking anticoagulants or suffering from coagulopathy

结局指标

主要结局

Frequency of bowel movement

次要结局

  • Abdominal pain

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

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