Engaging Higher-Order Mechanisms of Psychopathology: A Parsimonious Approach to Precision Medicine
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 39
- 试验地点
- 1
- 主要终点
- Change in clinician-rated borderline personality disorder symptoms
研究概览
简要总结
Participants with borderline personality disorder will undergo an a 2 - 4 week baseline assessment to determine level of outcomes of interest in the absence of treatment. After the baseline period, participants will receive six weekly 50-60-minute treatment sessions. After the 6 treatment sessions, participants will complete a 4-week follow-up period to determine the sustainability of the treatment module.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Speak English fluently
- •Diagnosis of Borderline Personality Disorder
排除标准
- •diagnosed psychological conditions that would be better addressed by alternative treatments
- •concurrent psychotherapy
- •medication instability
- •substance use disorder
研究组 & 干预措施
Personality-based treatment 2 week baseline
Participants will receive treatment tailored to 1 of 3 personality dimensions after a 2 week baseline assessment
干预措施: Personality-Based Therapy (Behavioral)
Personality-based treatment 4 week baseline
Participants will receive treatment tailored to 1 of 3 personality dimensions after a 4 week baseline assessment
干预措施: Personality-Based Therapy (Behavioral)
结局指标
主要结局
Change in clinician-rated borderline personality disorder symptoms
时间窗: up to 14 weeks (pre-baseline, pre-intervention, post-intervention, post-follow-up)
Change in borderline personality disorder symptoms will be measured using Zanarini Rating Scale for Borderline Personality Disorder (ZAN-BPD) - clinician-rated version. Scores range from 0-36; higher scores indicate greater severity of borderline personality disorder symptoms
Change in patient-reported borderline personality disorder symptoms
时间窗: weekly up to 14 weeks
Change in borderline personality disorder symptoms will be measured using Zanarini Rating Scale for Borderline Personality Disorder (ZAN-BPD) - self-report version. Scores range from 0-36; higher scores indicate greater severity of borderline personality disorder symptoms
次要结局
未报告次要终点
研究者
Shannon E. Sauer-Zavala
Associate Professor
University of Kentucky