Dermatologists' Educational Demonstration for Epiduo Application
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 85
- 试验地点
- 1
- 主要终点
- Percentile reduction of non-inflammatory & inflammatory acne lesions
研究概览
简要总结
The purpose of this study is to evaluate the efficacy and tolerability of this combination gel compared with BPO monotherapy in Korean patients, and test clinical practicability of dermatologists' educational demonstration for how to apply this gel in reducing uncomfortable irritations.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •mild to moderate acne were evaluated by Leeds revised acne grade from 2 to 6
- •age: 18-40
排除标准
- •pregnancy
- •mental illness
- •intake of oral isotretinoin within 6 months
- •application of the other oral or topical acne medications
- •chemical peeling or light based treatments within 6 weeks.
研究组 & 干预措施
Epiduo- dermatologist's detailed instruction
After randomly assigned to side of epiduo application, half of total patients were also re-assigned into detailed instruction for application of epiduo from dermatologist
干预措施: Epiduo once daily with detailed instruction for how to apply it (Drug)
Epiduo- drug insert only gruop
After randomly assigned to side of epiduo application, half of total patients were also re-assigned into drug insert only group
干预措施: Epiduo- once daily, simple instruction for application (Drug)
BPO group
After randomly assigned to side of BPO application, patients apply BPO during 12 week
干预措施: BPO once daily (Drug)
结局指标
主要结局
Percentile reduction of non-inflammatory & inflammatory acne lesions
时间窗: 12 weeks
Measurement of decreases in both non-inflammatory \& inflammatory acne lesions
次要结局
- Total number of local irriation effect counts (erythema, scaling, dryness, itching)(12 week)
研究者
Dae Hun Suh
Professor
Seoul National University Hospital