COVID-19 and liver injury in patients with or without underlying liver disease: A multi-centre retrospective-prospective observational study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 314
- 试验地点
- 1
- 主要终点
- •Prevalence of liver injury in patients infected with SARS-CoV-2 virus.
研究概览
简要总结
COVID-19 and liverinjury in patients with or without underlying liver disease: A multi-centreretrospective-prospective observational studyAll patients infected with SARS-CoV-2 and admitted to theCOVID-19 ward/ICU of Max Hospital Saket (either in East Wing , Max Super Specialty Hospital,Saket or MAX Smart Super Specialty Hospital, Saket) between 1/4/2020 to30/6/2020 (retrospective data between 1/4/2020- 30/5/2020 & prospectivedata from approval till 30/6/2020), will be included and measure outcomes Prevalence of liver injury in patientsinfected with SARS-CoV-2 virus and Prevalence of new liver injury in patients havingCOVD-19 infection over underlying liver diseases as a primary outcomes and Incidence of Acute liver failure, Incidence of ACLF and Mortality as secondary outcome
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 75.00 Year(s)（—）
- 性别
- All
入选标准
- •All patients infected with SARS-CoV-2 and admitted to the COVID-19 ward/ICU of Max Hospital Saket (either in East Wing , Max Super Specialty Hospital, Saket or MAX Smart Super Specialty Hospital, Saket) between 1/4/2020 to 30/6/2020 (retrospective data between 1/4/2020- 30/4/2020 & prospective data from approval till 30/6/2020), will be included.
排除标准
- •1.Patients less that 18 years old with COVID-19 2.Pregnant ladies with COVD-19
- •Unwilling to give consent for inclusion.
结局指标
主要结局
•Prevalence of liver injury in patients infected with SARS-CoV-2 virus.
时间窗: 4 weeks
•Prevalence of new liver injury in patients having COVD-19 infection over underlying liver dis-eases.
时间窗: 4 weeks
次要结局
- •Incidence of Acute liver failure(•Incidence of ACLF)